CREOSOTE 351 



C. Slightly soluble in water. It is miscible with alcohol, ether, fixed and vola- 

 tile oils. 



Dose.— H., Tri,v-xv, (.3-1); D., ni,ss-ii, (.08-.12). 



Action and Uses. — The action of creosote upon animals is practi- 

 cally the same as that of carbolic acid in kind, but is much less toxic. 

 The antidotes and treatment of poisoning are also similar. 



Externally, creosote is as effective a germicide as carbolic acid, but 

 the latter is usually preferred, being much cheaper. Creosote may be 

 applied in the same strength for its local antiseptic, parasiticide, and local 

 anesthetic action. It is employed in skin diseases and especially those of 

 parasitic origin. In scab 1 part is dissolved in 65 parts of 50 per cent, 

 alcohol, and in follicular mange of dogs it may be applied as follows : 



Creosoti 311. 



Potassii hydroxidi gss. 



Olei gossypii sem giilss. 



M. 



S. Apply externally. 



Internally, creosote is administered, as is carbolic acid, to check 

 vomiting and to act as an intestinal antiseptic in indigestion with fer- 

 mentation and diarrhea. Creosote is of much service as an inhalation 

 (in, XX. to Oi. of boiling water) in sub-acute bronchitis, in fetid nasal 

 discharge and in gangrene of the lung in horses. It is also given inter- 

 nally in chronic bronchitis and in distemper of dogs. It is eliminated to 

 some extent by the lungs and may act as an antiseptic in the lungs and 

 digestive tract and have a favorable stimulant, expectorant action. 



Distemper, dog. 



Creosoti (beechwood) ni,xxi. 



Bismuthi subcarbonatis 3iiss. 



M. et divide in capsulas No. xxi. 

 S. One three times daily. 



It is occasionally given by intratracheal injection (creosote, TTLx. in 

 § ss. of 60 per cent, alcohol) in gangrenous pneumonia of horses and to 

 sheep and calves in the same manner in parasitic bronchitis (TTtv. in 5 i. 

 50 per cent, alcohol). It may also be given by the mouth in verminous 

 bronchitis to kill the lung worms or by means of its elimination from 

 the bronchial mucous membrane. Neumann advises creosote (§ii.), ben- 

 zine (5 X.), and water (2 qts.) ; of the mixture for sheep, 1 teaspoonful 

 daily, by the mouth, for 8 days for verminous bronchitis. Chloroform in- 

 halation to a point where the animal staggers, followed by a purge, is 

 more satisfactory. 



Cresol. Trikresol. C,HsO. (U. S. P.) 

 Synonym. — Cresolum, cresylic acid, E.; cresol, Fr.; kresol, trikresol, G. 

 A mixture of isomeric cresols obtained from coal tar. Preserve it in amber- 

 colored bottles from the light. Cresol occurs as a colorless or yellowish to brown- 

 yellow, highly refractive liquid, becoming darker or assuming a reddish tint with 

 age and on exposure to light, aud having a phenol-like, sometimes empyreumatic 

 odor. Soluble in about 60 parts of water, usually forming a cloudy solution; it 



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