354 VEGETABLE DRUGS 



of water, and in 0.8 part of alcohol, 0.7 part of chloroform, and in 7 parts of 

 glycerin. 



Dose. — Same as quinine sulphate.f 



Quinine Valebas. Quinine Valerate. CzoHj^NjOjCjHioOa+HjO. (B. P.) 



(ISf on-official.) 

 Derivation. — Made by decomposition of quinine sulphate with ammonia, fol- 

 lowed by the immediate action of Valerianic acid, and crystallization from a cold 

 solution. 



Properties. — White, or nearly white, pearly, lustrous, triclinic crystals, having 

 a slight odor of valerianic acid, and a bitter taste. Permanent in the air. Soluble 

 in 100 parts of cold water, and in 5 parts of alcohol; in 40 parts of boiling water, 

 and in 1 part of alcohol. 



Dose. — D., gr.i-ii, (.06-.12). Three times daily as tonic. 

 Quinine et Ure^ Hydeochlohidum. Quinine and Urea Hydrochloride. 



(U. S. P.) 

 C»H2.0,N2HC1, CO(NH2)=HCl-|-5 H^O. 

 Synonym. — Quininae Bimuriatis carbamas. Quinine and urea bimuriate. 

 Prepared by dissolving quinine hydrochloride, 400, in dilute HCl, 300; mixing 

 with 60 to 61 parts of urea C0(NHj)2; warming, filtering and allowing to crys- 

 tallize. Occurs in colorless, translucent prisms, or as a white, granular powder, 

 odorless and having a very bitter taste. Permanent in the air. Soluble in 0.9 

 part of water and in 2.4 parts of alcohol. 



Chinoidixum or Quinoidinum. Chinoidine or Quinoidine. 

 Brown, resinous mass, containing mixture of quinidine, cinchonine and cin- 

 clionidine. A cheap substitute for quinine sulphate. 



Dose. — Three or four times that of quinine sulphate. 



Quinidine Sulphas. Quinidine Sulphate. (CaiHinNjOj)^, H2S04-(-2 HjO. 



(Non-Official.) 

 The neutral sulphate of an alkaloid obtained from the bark of several species 

 of cinchona (nat. ord. Rubiaceae). 



Synonym. — Sulfate de quinidine, Fr.; schwefelsaures chinidin (cinchinin), G. 

 Derivation. — Recovered from quinoidine, or from the mother liquors after 

 the crystallization of quinine sulphate, by the same method as for quinine. 



Properties. — White, silky needles, odorless, and having a very bitter taste; 

 jiermanent in the air. Soluble in 100 parts of cold water, and in 8 parts of 

 alcohol; in 7 parts of boiling water, and very soluble in boiling alcohol; also in 

 14 parts of chloroform and in acidulated water ; almost insoluble in ether. 

 Dose. — One-third larger than quinine sulphate. 

 CiNCHONiN.E Sulphas. Cinchonine Sulphate. (CijH^^ON.,)^ H,S04-f2 



(U. S. P.) 

 DericoiJon.— Obtained from the mother liquors after the crystallization of the 

 Fulphates of quinine, quinidine and cinchonidine, by precipitation with caustic 

 soda, washing with alcohol to free it from other alkaloids, solution in sulphuric 

 acid, and by purification with animal charcoal, and crystallization. 



Properties. — White, lustrous, prismatic crystals, odorless and having a very 

 bitter taste. Permanent in the air. Soluble in 60 parts of water, and in 12.5 

 parts of alcohol. Also soluble in 47 parts of chloroform, but almost Insoluble in 

 ether. 



Dose. — One-third larger than that of quinine sulphate. 

 CiircHONiDiN.E Sulphas. Cinchonidine Sulphate.* (Ci„H2,NjO)2 H3SO4-I-3 H2O. 



(U. S. P.) 

 Dirivation. — Procured from the mother liquors, after the crystallization of 



fQuinin(e Salicylas, Quinine Salicylate (U. S. P.). Soluble in 77 parts of 

 water. Occurs in colorless needles. Dose as for sulphate. 



*Elixir Ferri, Quirdnw et Strychninw Phosphatum (U. S. P.), and Syrupus 

 Ferri Phosphatis cum Quinina et Strychnina (B. P.), (dose — D., 3i), are good 

 tonic preparations for dogs. 



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