554 



GENERAL THERAPEUTIC MEASURES 



6. For cattle which are apparently healthy, and which have not 

 been injected with tuberculin within a period of at least 60 days, the dose 

 of tuberculin prepared by the Bureau of Animal Industry is as follows : 



Two mils for calves ranging from six months to one 



year of age. 

 Four mils for cattle more than 1 year old to maturity. 

 Older animals or animals clinically suspicious may 



receive a larger dose. 



7. The measurements of temperature following the injection of 

 tuberculin should commence at the eighth hour and be continued every 

 two hours until the twentieth hour after injection, when, if there is no 

 tendency for the temperature to rise, the test may cease. Temperatures 

 upon cattle which are showing a rising tendency following the injection 

 of tuberculin should be measured more frequently. 



8. Suspected cattle should be submitted to a retest after the expira- 

 tion of not less than 60 days. This class of cattle and those which show 

 possible physical evidences of tuberculosis, emaciation, old age, or which 

 have been tested repeatedly should receive double the dose of tuberculin 

 indicated above. 



9. Experience has shown that animals, especiallj^ those of doubtful 

 record, re- 

 c e i V i n g 

 large doses 

 of tubercu- 

 lin, may re- 

 spond early 

 to the test, 

 and inspec- 

 tors are ad- 

 vised, 

 w h e r ever 

 practicable, 

 to o b t ain 

 temp era- 

 t u r e s at 

 from the 



fourth to sixth hour following th 3 use of large doses of tuberculin. 



10. A rise of 2° F., or more, above the maximum temperature ob- 

 served prior to the injection of tuberculin, or a temperature above 103.8° 

 F., should be regarded as an indication of tuberculosis, provided the tem- 

 perature reaction shows the characteristic rainbow curve. 



11. Animals which after injection show a rise of temperature of 2° 

 F., with a maximum of between 103° and 103.8° F., as well as those 

 which show a rise of less than 2° F., with a maximum temperature of 

 103.8° F., are regarded as suspicious. The presence of a general systemic 

 reaction or a typical curve should be eonsidered in determining the classi- 

 fication between suspects and reactors. 



The Intradermal Test. 

 The intradermal test is not officially recognized by the U S Bureau 

 of Animal Industry, ^j^g^e""^ ^f^l^oSbW '^^"l^ °' ^"^^^^ ^^ose 



An Unusually Well Defined Reaction to the Intradermal Tuberculin 



Test 



