DOCUMENTS 339 



asked me to give him a second injection. This I. gave him at 

 2.2^ p.m. (5 c.c). 



" Date on bottle used, May 8, 1900. 



" The pains in the joints had disappeared on the second injection 

 (which was given in opposite flank) . At 5 o'clock the man walked 

 away with assistance. He was quite well a couple of hfturs 

 after the second injection, and when I saw him again on May 8 

 he was in perfect health." 



G. — European Yipers {Pelias berus and Vipera aspis). 



XX. — Case published by Dr. Marchand, of des Montils, Loir-et- 

 Cher {Anjou medical, August, 1897). 



" About 11 a.m., on Friday, July 23, Jules Bellier, aged 26, was 

 mowing in a damp spot, when he was bitten in the heel by a laifge 

 viper {Vipera berus). The bite, which was deep, was situated on 

 the outside of the foot, 1 cm. behind the malleolus and 3 cm. above 

 the plantar margin ; at this point there were two punctures in the 

 skin, 1 cm. apart. Directly after the accident the patient left his 

 work, tied his hankerchief tightly round the lower third of his leg, 

 made the wound bleed, and came to me with all speed, hopping on 

 one foot for about a kilometre. When I saw him scarcely twenty 

 minutes had elapsed since the accident ; his general appearance was 

 altered, and his pulse rapid. The patient had vomited twice ; he 

 complained of pains in the head, and of general weakness, and 

 ' was afraid,' he said, ' of fainting.' The foot and leg were painful 

 under pressure; a slight tumefaction was visible in the peri- 

 malleolar region, around the bites, which bled a little. Forthwith, 

 after washing the wound freely with a solution of permanganate 

 of potash, I injected 10 c.c. of Calmette's serum into the antero- 

 external region of the middle part of the thigh ; then I enveloped 

 the leg in' a damp antiseptic dressing as high as the knee. The 

 patient breathed more freely and plucked up his spirits. After 

 lying down for quarter of an hour he went home on foot (he lives a 

 hundred yards from my house). 



