20 PRINCIPLES OF VETERINARY SURGERY 



in the blood-vessels gives place to a renewed circulation, the 

 corpuscles of the stagnant blood one by one moving off until 

 a slow stream is established through the inflamed area. The 

 stream quickens, and the normal contraction of the vessels 

 is restored. Thus the heat and swelling of the injured part 

 are reduced, and finally complete repair takes place. 



The foregoing processes are characteristic changes which 

 accompany the healing of slight wounds only; in case of se- 

 vere wounds or deep cuts with the surgeon's knife, much 

 tissue is destroyed and there is usually an abundant hemor- 

 rhage into the part, which forms a clot temporarily filling 

 up the wound. The repair which follows is in essence the 

 same as takes place in slight injuries, only much more tissue 

 has been destroyed and therefore much more must be re- 

 generated. 



HEALING OF AN INCISED WOUND.— In case 

 a large amount of tissue has been destroyed, as 

 would occur in an incised wound, or in an exten- 

 sive surgical operation, the gap in the tissue fills up 

 with clotted blood, which forms a temporary bridge 

 between the divided parts and makes a path for the 

 regenerating tissue cells as soon as they begin to multiply. 

 The endotheHal cells of the vessek, and the old connective 

 tissue cells in the parts adjacent to the edges of the wound 

 throw out protoplasmic processes and invade the blood-clot. 

 New connective tissue cells are formed from the old, which 

 possess independent locomotion or ameboid movement, and 

 they move about in the fibrinous meshes of the clot, throw- 

 ing out a fibrous stroma until finally a firmer bridge of young 

 connective tissue is formed. Simultaneously new capillaries 

 sprout from the old, and nourish the newly formed con- 

 nective tissue, or granulation tissue so-called. This granu- 

 lation tissue is characterized by many different varieties of 

 cells. The proliferating connective tissue cell is present in all 



