PRINCIPLES OF VETERINARY SURGERY 89 



iology, — was the demonstrations of Sir Joseph Lister in the 

 treatment, or rather the prevention, of wound diseases. These 

 investigations began in i865-:and were perfected by investi- 

 gations from time to timie, until the present day. Lister 

 proved that the miserable behavior of wounds was due to 

 intruding microbes, and that by excluding them the healing 

 occurred by the simple, uncomplicated process that is today 

 known as "reparative hyperaemia," or simple inflammation. 



While the evolution of bacteriology cannot be discussed 

 at length here, it is only fair to recognize the valuable work 

 of Guerin, Tyndal, Kircher, Klebs, Koch, Behring, Weigert, 

 Gram, Kitasato, Nicolaier, Shultz, Rosenbach, Arloing, Cha- 

 veau, Moore, Bollinger and many others, all of whom have 

 added much to the store-house of modern bacteriological 

 knowledge. 



At the present day, however, many questions remain to 

 be solved, and although a great number of specific bacteria 

 have been discovered, much remains to be learned as to the 

 therapeutic management of the diseases they produce. And 

 besides, there are still many diseases known to be of bac- 

 teria] origin, in which the specific agent defies discovery in 

 spite of the modern methods of investigation and the many 

 instructive precedents to follow. Although bacteriology has 

 given us but few cures, it has furnished many an impressive 

 lesson in prophylaxis. Diphtheria antitoxin is really the only 

 specific curative weapon it has furnished todate. Mallein is 

 credited with marked curative properties in equine glanders, 

 and tuberculin is said by many to possess analogous effects 

 in human and bovine tuberculosis, but additional data seems 

 necessary to establish these facts beyond doubt. Anthrax, 

 rabies, glanders, symptomatic anthrax, tick fever and teta- 

 nus are prevented by artificial immunization, and disinfec- 

 tion, isolation, quarantine and hygiene, owing to a better 

 knowledge of etiology, can be more intelligently utilized. 



