392 



PRINCIPLES OF VETERINARY SURGERY 



imentation that was methodical and rational. They classed 

 domestic species in order of receptivity : 



Man 



Horse 



Donkey 



Sheep 



Hog 



Dog 



9 



lO 



] I 



12 



Cat 



Cavy 



White rat 



Rabbit (average receptivity) 



Chicken 



Duck 



The inoculation of the frog by introducing the virus into 

 the dorsal lymphatic sac is followed by no noticeable results, 

 but if the aquarium is heated to 26 to 28 degrees C. the frog 

 dies in two or three days, and comes floating to the surface 

 all bloated with gas. 



When inoculated in the connective tissue of the skin, the 



Fig. 38. 

 Culture of Septic Vibrio in Gelose after 24 hours at 34' C. (Frankel.) 



sheep becomes lame the succeeding day, and on the days 

 following the inoculated limb is hot and tumefied; then the 

 oedema spreads and the animal dies. In solipeds the prog- 

 ress of the disease is about the same. In birds there is an 

 extremely abundant cedema rather than gaseous infiltration. 

 From injections in the areolar tissue the cavy survives twen- 

 ty-four to twenty-six hours ; the dog four to six days ; the 

 ass two to three days ; and the sheep two to eight days, 

 and often succumbs earlier. Intravenous injections in doses 

 of two to forty drops in whatever species or condition are 

 never fatal. A dog injected with sixteen cubic centimetei^s 

 of a virulent pure culture was not incommoded, but appeared 

 more refractory from a subcutaneous inoculation. From in- 

 tra-arterial injecJ;ions the results are the same. Through the 



