PRINCIPLES OF VETERINARY SURGERY 485 



to 5 c.c. for the small animals — sheep, goats and hogs. Two 

 injections are made at intervals of twelve days. The im- 

 munity, although transient — two to six weeks duration — is 

 sufficient to carry the subject safely over the period of cica- 

 trization to the infected wound. For wounds of a longer 

 duration, a third or fourth injection must be made. The 

 serum causes no inconvenience. It is as harmless as it is 

 effectual. 



It is supplied by the Pasteur Institute of Paris in bottles 

 containing- lo to 20 c.c. The firm of Meister, Lucius & Brun- 

 ing, of Hochst-on-the-Main, furnishes desiccated serum that 

 is used in 5-gram doses dissolved in 45 c.c. of distilled water. 



ANNOTATION. 



Besides the Pasteur Company, which has distributing offices in all the 

 principal American cities, the serum can also be obtained in America from 

 Mumford & Co., of Philadelphia, and from Parke, Davis & Co., of Detroit, 

 Mich.— L. A. M. 



Curative Treatment. — The most varied treatments have 

 been recommended against tetanus. Their number and di- 

 versity shows their inefficiency. The fact is, in spite of in- 

 numerable attempts, no agent has been found capable of 

 hindering' the progress of confirmed tetanus. There is noth- 

 ing more uncertain than the treatment of tetanus. It is use- 

 less to recall all the expedients that have been successively 

 extolled. Recoveries have occurred under the influence of 

 a variety of different medicines : in reality it cures itself. 

 The medicines have counted for nothing in the matter. 



The most rational treatment based on the theoretical 

 knowledge acquired during the last few years as to its eti- 

 ology and pathogenesis, is both local and general. 



Local treatment is directed toward the suppression of 

 the bacterian hot-bed. Its object is to destroy the micro- 

 organisms that produce the toxin. This recommendation 

 may be effected by different surgical expedients : cauteriza- 

 tion, ablation, amputation, disinfection, etc. The ablation 



