558 PRINCIPLES OF VETERINARY SURGERY 



of bone, sparing the bone cells. Attention has been drawn 

 to melanosis of the skin and the meninges, which are occa- 

 sionally as black as ink, or melanosis of the viscera. Mus- 

 cular pigmentation has been observed by Gotz, in the heart, 

 the muscles of mastication and the tongue, which exhibited 

 a deep brown color. This black matter in the flesh would 

 proceed, according to Rabe and Schultz, from a pigment- 

 ary infiltration in the connective tissue. The same authors 

 have also found similar alterations in the liver of an ox, that 

 presented lesions of chronic hepatitis. 



Cases of generalized melanosis are not extremely rare. 

 Albert observed a case in which the muscles, the paren- 

 chymatous organs and the dorsal and lumbar vertebrae had 

 undergone melanotic pigmentation, and Nuvoletti refers 

 to a case of generalized melanosis in a cow exhibiting num- 

 erous tumors, first in the subcutem, then in the muscles of 

 the thigh, shoulders and back; in the intermuscular connec- 

 tive tissue and in the peritoneum and walls of the intestines. 

 The spleen contained a melanotic tumor as large as the fist, 

 and the diaphragm and pleura were studded with them. 

 Analogous tumors have likewise been observed in the 

 region of the elbow joint, and in various other regions. 

 Nuvoletti found a three-year-old ox that exhibited blackish 

 stains of the viscera, pleura, Schniederian membrane and 

 subcutem. In 1885, Cadeac published the history of a case 

 of melanotic fibroma in the depths of the right buttocks, 

 and similar observation were reported by Cancel, who 

 found melanotic tumors in the pelvis of a cow. Hamberger 

 describes a tumor on the pleura of an ox that presented the 

 structure of a chondro-fibro-melano-sarcoma. 



Melanomata are frequently nothing more than mel- 

 anotic myxomata, as was shown by LaBlanc in the case of 

 a four-year-old cow, exhibiting a tumor having the consist- 

 ency of a myxoma, in the abdominal wall, which, when but 



