452 ACTIN03IYCETE8. 



orange color. It is not pathogenic for animals. The 

 actinomyces aurantiacus (Rossi Doria) Gasperini is 

 similar. 



Actinomyces madurae. (Vincent.) Lehm. and Neum. 



Streptothrix maduraj Vincent (A. P., 1894, 129). 



There is great similarity to actinomycosis in the course 

 of the disease known as ' ' madura-foot, madura-boil, 

 Dehli-boil" (first brawny, then nodular, usually perfor- 

 ating externally). It is a disease, affecting especially the 

 feet and hands, which is native to India, but also occurs 

 in northern Africa, Italy, etc. Our description is from 

 Vincent. In the pus from the fistulse there are found 

 bodies (gray, yellow, black) similar to those of actino- 

 mycosis, which, according to Kanthack's illustrations, 

 have the same structure as actinomyces granules. 



The organisms are obligate aerobes, and grow excellently upon de- 

 coctions of potato, turnip, etc. , which have not been neutralized, with 

 the production of alkali. As the best solid nutrient medium, Vincent 

 employed a decoction of haj' or potato to which is added, for every 

 100 gm. of gelatin, 4 gm. of glycerin and 4 gm. of grape-sugar. Gela^ 

 tin is not liquefied. Old gelatin cultures resemble a vaccine pustule, 

 being dry, closely attached to the nutrient medium, somewhat de- 

 pressed in the middle, whitish, the periphery red. Upon potatoes 

 whitish-red prominences, which often present an air mycelium with 

 conidia ; also in other mj'celium, spore-formation occurs. There is no 

 musty odor. ' The spores die in three minutes at 85° and in five 

 minutes at 75°. The cultures with no spores die at 60° in from three 

 to five minutes. The threads and conidia stain readily VFith all the 

 anilin dyes and by Gram's method. It is not pathogenic for animals 

 (rabbits, guinea-pigs, mice, cats). 



Actinomyces chromogenes. Qasperini. 



(Plate 67.) 



Synonyms. 1 — Streistothrix chromogena Gasperini, 

 Oospora Metschnikovi Sauvageau and Radais,^ Strepto- 

 thrix nigra Doria. Cladothrix dichotoma Mace, Giinther 



1 "We describe a variety isolated by ourselves ; the synonyms we have 

 determined in part from comparison with the descriptions, in part from 

 the cultures. 



^ Sauvageau and Eadias could not find spores in their Streptothrix 

 MetsohnikoviL 



