Diseases of the Nesvous System. 257 
some of the pathological alterations were so frequent that 
they could be accurately grouped, yet others were so in- 
constant that there could not be said to be any certain 
indication of the presence of the disease. In some were 
found alterations in the brain ; in others, changes in the 
blood, lymphatic glands, and kidneys; and in others, 
- morbid manifestations in the digestive organs were met 
with. The malady prevailed as an epizooty, and animals 
. of both sexes, various ages and breeds, when or whether 
bitten often unknown, were at different times brought to the 
Institute. Frequently little could be learned with regard 
to the animals which were brought dead, and even their 
condition previous to death could rarely be ascertained. 
With regard to the value of some pathological alterations 
in forming a judgment as to the presence of the disease, 
the following epitome is given of the result of the necrosco- 
pical examinations made of these animals: 
a. Alterations in the brain. 1. Hemorrhage into the 
subcutaneous tissue of the cranium of a suspected dog. 
2. Hemorrhage into the dura mater of two rabid and one 
suspected animals. 3. Injection of the pia mater and 
plexus chorides in 28 rabid and 2 suspected. 4. Hyperemia 
of the brain in 2 rabid. 5. Softening of the brain in various 
degrees—from mere shining softness (glazend und weicher 
sein) to complete pulpy liquefaction—in 35 rabid and 2 
suspected animals (of these the whole brain was generally 
involved in 3 rabid cases; the cerebellum in 3 rabid, and 
2 suspected ; the upper surface and base of the brain in I 
rabid animal. 6. Distension of the lateral ventricles, 
through a collection of serum therein, in 10 rabid animals, 
1 of which had the right ventricle unusually dilated, while 
the left was normal. 
4. Alterations in the circulatory apparatus and the blood. 
1. Pericarditis in 1 suspected dog. 2. Capillary haemorrhage 
into the pericardium in 2 rabid cases. 3. Hemorrhage 
beneath the endocardium in 1 rabid case. 4. Alterations 
