Diseases of the Nervous System. 261 
proved; but that it has some foundation in fact may be 
deduced by reference to the extensive derangement in the 
other nerve regions, particularly in the branch of the fifth 
pair supplying the lower jaw. 
Alterations in the ophthalmic branch are likewise few 
when those of the maxillary are so—proving, apparently, 
that the lesion is central. 
According to Professor Benedikt (“Wiener Med. Presse,” 
No. 74)* the disease is a special acute exudative inflam- 
mation of the brain, resulting in various forms of hyaloid 
degeneration, which is particularly observed in the neigh- 
bourhood of the lenticular nucleus of the anterior lobe— 
often in this alone. Siedamgrotzky states that he has, in 
his examinations, been particularly careful to inquire into 
the correctness of this; and in some cases of “dumb mad- 
ness” there was certainly a marked inflammatory condition 
of a portion of the brain about the fissure of Sylvius. 
In the “Giornale di Anatomia,” etc., edited by the 
veterinary professors at the University of Pisa, Rivolta 
gives the description of a careful examination he made of 
the brains of seven dogs which had perished from furious 
rabies transmitted to them by inoculation. The result 
goes to show that the pathological alterations in that organ © 
consist mainly in more or less marked hyperemia of the 
pia mater in the cerebral fissures, but especially at the base 
of the brain, and this hyperemia is never absent from the 
cerebral plexus choroides; that softening of the cerebral 
substance is not frequent, though, on the contrary, the grey. 
substance is constantly higher coloured ; and that perivas- 
cular infiltration of a fatty nature cannot be recognised as 
characteristic of this disease, as Rivolta has noticed it in 
other maladies.t 
In the “ Centralblatt. fiir die Medicin-Wissenschaften,” 
*From the ‘‘ Veterinary Journal,” October, 1876 
t Ibid. t Ibid. 
