306 The Management and Diseases of the Dog. 
“Of these observers, Dr. Sanderson points out that Dr. 
Letzerich,* of Braunfels (Nassau), and Dr. Oertel,t of Mu- 
nich, are most important. The former is the author of 
several papers on diphtheria, the titles of which are given ~ 
in anote. These papers contain various observations re- 
lating to diphtheria as it presents itself clinically, and serve 
to illustrate the intimate association of the development of 
microzymes in the affected parts with the morbid process ; 
the author also records numerous experiments showing that 
when the disease is communicated by inoculation, its 
characteristics reappear in the infected animal, even those 
which belong to its more remote complications. 
“Dr. Letzerich’s facts lose much of their value, according 
to Sanderson, from their not being set down with that sim- 
plicity which ought to characterise all scientific writings. 
His papers, moreover, contain a great deal of questionable 
mycology, in which the patient reader is apt to lose himself 
in his search after objective facts. 
“The Mémoire of Dr. Oertel, published three years ago, 
also embodies anatomical and experimental investigations 
relating to the effect of inoculating animals with material 
derived from the larynx in cases of diphtheritic laryngitis 
in children. Like Letzerich, the author found that a 
disease having well-defined pathological characteristics, and 
in particular, associated with nephritis, could be produced 
by such inoculation ; and further, that it could be commu- 
nicated from one animal to another without losing any of 
its distinctive features. He further showed that the disease 
in question, whatever were the local peculiarities given to 
it by the tissue in which it was ingrafted, was always a 
mycosis ; in other words, that all the ‘localisations’ of the 
* Letzerich, “ Beitrage zur Kenutnisf der Diphtheritis,” ‘‘ Virchow’s 
Archiv.,” vols. xlv. p. 327; xlvi. p.229; xlvii. p. 516. ‘* Monographie 
der Diphtherie,” Berlin, 1872, ‘‘Die Entwickelung des Diphtherie- 
pilzes,” ‘* Virchow’s Archiv.,” vol. lviii. p. 303 (1873). : 
+ Oertel, “‘Experimentelle Untersuchungen iiber Diphtherie ; ” 
** Deutsches Archiv. fiir Klin. Med.,” vol. viii. pp. 242—354. 
