308 Lhe Management and Diseases of the Dog. 
‘On an examination of the body, it was discovered that in 
the swollen baggy part of the skin where the inoculations 
had been made, there was fibrous infiltration of the subcuta- 
neous connective tissue, with hemorrhagic patchesof a bluish- 
black or dirty light-red colour, that passed deep into the 
muscles of the back. In the abdominal muscles attached 
to the spine, as well as in the peritoneum, there were also a 
few isolated patches, generally running into each other in 
an irregular manner. In the connective tissue of this 
region were many marked hemorrhagic patches, and they 
were all related more or less to others in the connective, 
tissue surrounding the left kidney. This organ exhibited 
on the infero-external portion, which was in contact with 
the lumbar region, a circular, eroded, haemorrhagic spot, 
about the size of a rather large pea. The liver was 
reddish-brown in colour, and very much enlarged and 
indurated. The spleen was aiso enlarged, very full of blood, 
and its parenchyma softened. The heart was softened, and 
its texture very light-coloured. The lungs were healthy, 
but the stomach and intestines were somewhat swollen ; 
the stomach was empty, and the small intestines nearly so ; 
the large intestines contained a quantity of fluid feces, but _ 
no scybala. The right lumbar region was normal, and the 
right kidney large and light-coloured. The bladder con- 
tained a small quantity of muddy urine. 
“A colleague of Dr. Letzerich made a most careful and 
interesting histological examination of the body, and found 
at the seat of inoculation, in the wedge-shaped exudate 
formed at the punctures and wounds, bacteria and plasma- 
globules (p/asma-kugeln) closely agglomerated, the latter 
‘being in a finely granular condition. In a prepared section 
of the skin it was noted that the sheaths of the hair in . 
various parts were full of bacteria, micrococci vesicles, and 
plasma-globules. In the texture of the skin itself were 
numerous masses of bacteria and plasma-globules, as well 
as clusters of micrococci. In the vicinity of those muscles ~ 
