General Dzseases. 353: 
and guarded from all friction. Ifthe general character of 
the pustules is considered, it will be observed that, while 
some of them are in a state of serous secretion, others will 
only have begun to appear. 
“ The eruption terminates when desiccation commences 
in the first pustules; and, if some red spots show them- 
selves at that period of the malady, they disappear without 
being followed by the development of pustules. They are 
a species of abortive pustules. After the desiccation, the 
skin remains covered by brown spots, which, by degrees, 
die away. There remains no trace of the disease, except 
a few superficial cicatrices, on which the hair does not grow. 
“The causes which produce the greatest variation in the 
periods of the eruption are, the age of the dog and the tem- 
perature of the situation and of the season. The eruption 
runs through its different stages with much more rapidity 
in dogs from one to five months old, than in those of 
greater age. I have never seen it in dogs more than 18 
monthsold. An elevated temperature singularly favours 
the eruption, and also renders it confluent and ofa serous 
character. A cold atmosphere is unfavourable to the erup- 
tion, or even prevents it altogether. Death is almost con- 
stantly the result ofthe exposure of dogs having small-pox 
to any considerable degree of cold. A moderate tempera- 
ture is most favourable to the recovery of the animal. A 
frequent renewal or change of air, the temperature remain- 
ing nearly the same, is highly favourable to the patient ; 
consequently, close boxes or kennels should be altogether 
avoided. \ 
“T have often observed that the perspiration or breath of 
dogs labouring under variola emits a very unpleasant odour. 
This smell is particularly observed at the commencement 
of the desiccation of the pustules, and when the animals are 
lying upon dry straw; for the friction of the bed against 
the pustules destroys their pellicles and permits the purulent 
matter to escape—and the influence of this purulent matter 
