OF THE HUMAN SKIN. 39 



Gralap, Benedictus, Paracelsus, Ambrose Par6, 

 Scaliger, Fallopius, Joubertus, Vidius, Schenck, 

 Haffenreffer, Eiolanus, Mouffet, and many others. 

 These names carry us down to the early part of 

 the seventeenth century, to Jansen's discovery of 

 the microscope, in 1619. The knowledge of the 

 use of the then primitive instrument soon spread, 

 and the itch-mite was studied by it, the first 

 rough drawing of the animal being given by 

 Hauptmann. During this (the sevententh) cen- 

 tury, the various writers on medical topics show 

 more or less knowledge of this mite. We will 

 not, however, tire our readers by quoting their 

 names. Some of them mention the custom, 

 which has been a common practice from that day 

 to this, of extracting the itch-mite from the skia 

 by means of a needle. Although, by this time, 

 the mite had been depicted, and its association 

 with the itch disease recognized, yet it was not 

 till 1687 that Dr. Bonomo, of Leghorn, and Ces- 

 toni, an apothecary, studied our little friend ia 

 what we should now call a commwn-sense way, 

 and thoroughly exploded the old ideas, handed 

 down from one generation to another, that the 

 itch-disease was due to thickened bile, drying of 



