194 ACTION OF SALTS. 
eight per cent, and are destroyed by five hours’ exposure to 9.23 per 
cent (Kitasato). Antiseptic in the proportion of 1:7 (Miquel). 
Potassium Permanganate.—In the writer’s experiments (1881) 
a two-per-cent solution was required to destroy Micrococcus Pasteuri 
in the blood of a rabbit. In later experiments pus cocci in bouillon 
were killed by 1 :833—time of exposure two hours. One per cent 
was found by Koch not to destroy anthrax spores in two days, but 
five per cent was effective in one day. The glanders bacillus is de- 
stroyed in two minutes by a one-per-cent solution (Léffler). The 
experiments of Jager show that a one-per-cent solution is not reli- 
able for the destruction of anthrax bacilli and other pathogenic bac- 
teria tested, but a five-per-cent solution was effective. The tubercle 
bacillus was not, however, killed by exposure in a five-per-cent solu- 
tion. According to Miquel, permanganate of potash is an antiseptic 
in the proportion of 1 : 285. 
Quinine Hydrobromate.—Antiseptic in the proportion of 1 : 182 
(Miquel). 
Quinine Hydrochlorate.—Antiseptic in the proportion of 1 : 900 
(Ceri). Quinine dissolved with hydrochloric acid destroys anthrax 
spores in ten days in one-per-cent solution (Koch). 
Quinine Sulphate.—The writer found that in the proportion of 
1: 800 quinine prevents the development of various micrococci and 
bacilli. A ten-per-cent solution does not destroy the bacilli of symp- 
tomatic anthrax (Arloing, Cornevin, and Thomas). 
Silver Nitrate.—Miquel places nitrate of silver next to mercuric 
chloride as an antiseptic, effective in the proportion of 1 :12,500. 
Behring also places it next to bichloride as an antiseptic and germi- 
cide, and says that it is even superior to this salt in albuminous 
fluids. He reports that it prevents the development of anthrax 
spores when present in a culture liquid in the proportion of 1: 80,000, 
and in the proportion of 1:10,000 destroys these spores in forty- 
eight hours, We give below the result of recent experiments by 
Boer, in which the time of exposure was two hours: 
Restrains Destroys 
development. vitality. 
Anthrax bacillus........... 0... c eee eee eee ; 1: 60000 1: 20000 
Diphtheria bacilius . 1: 60000 1: 2500 
Glanders bacillus.... 1: 75000 1: 4000 
Typhoid bacillus.......... 1: 50000 1: 4000 
Cholera spirillum..............0.-e eee eee 1: 50000 1: 4000 
Silver Chloride.—A solution of chloride of silver in hyposulphite 
of soda is much less effective as an antiseptic than nitrate of silver. 
