380 PYOGENIC BACTERIA. 
culating fluid, and in man, as in animals infected experimentally, a 
microscopic examination of the blood for microérganisms usually 
gives a negative result. Culture experiments may, however, demon- 
strate their presence. Thus recent investigations by Netter, Hisel- 
berg, and others show that the pus cocci are usually present in the 
blood in small numbers, as demonstrated by culture experiments, in 
septic infection from wounds. 
STAPHYLOCOCCUS PYOGENES ALBUS. 
Isolated by Rosenbach (1884) from the pus of acute abscesses, in 
which it is sometimes the only microdrganism present, and some- 
times associated with other pus cocci. In thirty-three acute abscesses 
examined by Passet (1885) it was associated with Staphylococcus 
aureus in eleven, with Staphylococcus citreus in two, with Strepto- 
coccus pyogenes in one, with both Staphylococcus citreus and Strep- 
tococcus pyogenes in one, and was obtained alone from four. 
In its morphology this micrococcus is identical with the preced- 
ing, but it is distinguished from it by the absence of pigment and 
by being somewhat less pathogenic. Surface cultures upon nutrient 
agar or potato have a milk-white color. It liquefies gelatin in the 
same way as does the golden staphylococcus, but the deposit at the 
bottom of the liquefied gelatin is without color. In the temperature 
conditions favorable to its growth, and in its biological characters 
generally, with the exceptions noted, it is not to be distinguished 
from the species previously described. According to Fliigge, it is 
more common than aureus among many of the lower animals. 
Pathogenesis.—Fortunati has tested the comparative pathogenic 
power of Staphylococcus aureus and Staphylococcus albus by inocu- 
lations into the cornea of rabbits. A. purulent infiltration of the 
cornea and panophthalmitis resulted when Staphylococcus aureus 
was inoculated upon the surface of the cornea by scratching with an 
infected needle, but inoculations made in the same way with Staphy- 
lococcus albus healed spontaneously or gave rise to a perforating 
ulcer. After paracentesis of the cornea with an instrument infected 
with Staphylococcus aureus panophthalmitis developed in thirty hours; 
the same result occurred at the end of sixty to seventy-two hours 
when the instrument was infected with Staphylococcus albus. When 
a sterilized instrument was used the result was negative. In bacteri- 
ological researches made by Gallenga, in cases of panophthalmitis in 
man, Staphylococcus albus was found in ten cultures and Staphy- 
lococcus aureus in nine. 
Staphylococcus Epidermidis Albus (Welch). 
The researches of Welch show that a white staphylococcus, prob- 
ably identical with Staphylococcus pyogenes albus of Rosenbach, is 
