520 BACILLI WHICH PRODUCE SEPTICMIA 
vomiting, or efforts to vomit. Death usually occurs at the end of two or 
three days. At the autopsy the spleen is found to be normal, the other or- 
gans slightly hyperzemic, and the intestinal mucous membrane in a state of 
éatarrhal inflammation. The bacilli are found in the blood and in the vari- 
ous organs in considerable numbers. 
PROTEUS CAPSULATUS SEPTICUS. 
Obtained by Banti (1888) from a case of ‘t acute hemorrhagic infection.” 
According to Banti, this is possibly identical with the preceding species— 
Proteus hominis capsulatus—but in some respects more nearly resembles 
Friedlinder’s bacillus. 
BACILLUS ENTERITIDIS. 
Obtained by Giirtner (1888) from the tissues of a cow which was killed in 
consequence of an attack characte1ized by a mucous diarrhoea, and also from 
the spleen of a man who died twelve hours after eating the flesh of this 
animal. 
Morphology.—Short bacilli, about twice as long as broad, frequently united 
in pairs; chains of four to six elements are sometimes seen. 
Stains with the usual aniline colors, and presents the peculiarity of 
staining deeply at one end while the remainder of the rod is but slightly 
stained. When two bacilli are united the deeply stained ends are in apposi- 
tion. 
Biological Characters.—An aérobic, non-liquefying, motile bacillus. 
Spore formation not determined. Grows in the usual culture media at the 
room temperature. Upon gelatin plates pale-gray, superficial colonies are 
formed at the end of twenty-four hours; under a low power these are seen 
to be coarsely granular and transparent; the central portion usually pre- 
sentsa greenish color ; deep colonies are spherical, indistinctly granular, 
and of a brownish color ; in older colonies a marginal transparent zone is 
seen which appears to be made up of minute fragments of glass of a pale- 
brown color. In gelatin stab cultures but slight development occurs along 
the line of puncture ; upon the surface a thick, grayish-white layer is 
formed, which after a time becomes very much wrinkled. Upon the surface 
of agar, at 37° C., at the end of eighteen to twenty hours a grayish-yellow 
layer has formed. Upon potato a moist, shining, yellowish-gray layer is 
developed. The growth upon blood serum is rapid in the form of a gray 
layer along the line of inoculation. 
Pathogenesis.—White mice and house mice usually die in from one to 
three days when fed with a pure culture of this bacillus. Rabbits and gui- 
nea-pigs die in from two to five days from subcutaneous injections—less 
pathogenic for pigeons and canary birds. Dogs, cats, chickens, and sparrows 
areimmune. A goat died in twenty hours after receiving an intravenous 
injection of two cubic centimetres of a culture in blood serum. The princi- 
pal pathological appearance consists in an intense inflammation of the in- 
testinal mucous membrane. The bacilli are found in blood from the heart 
and also in the contents of the stomach. 
BACILLUS OF GROUSE DISEASE. 
Obtained by Klein (1889) from the lungs and liver of grouse which had 
succumbed to an epidemic disease. 
Morphology.—Bacilli with rounded ends, from 0.8 to 1.6 «long; may 
also be seen as spherical or oval cells 0.6 4 long and 0.4 « thick; solitary, in 
pairs, or in chains of three to four elements. 
Stains best with Weigert’s solution of methylene blue in aniline water. 
Biological Characters.—An aérobic, non-liquefying, non-motile bacillus. 
Spore formation not observed. Grows in the usual culture media at the 
