NOT DESCRIBED IN PREVIOUS SECTIONS. 561 
logical products from man. It is distinguished from them by its pathogenic 
action upon mice. White and gray mice when infected with our bacillus 
die from septicaemia and show, in addition to a serous exudation at the point 
of inoculation, constant pathological changes in the kidneys, which may usu- 
ally be recognized by a macroscopic examination. Also by the spleen, which 
is not always enlarged, and the liver, which only in a few cases showed any 
microscopic changes. In mice inoculated with the bacillus of Fasching, or 
that of Abel, which died of septicae:mia, there was constantly seen an en- 
largement of the spleen (Fasching, Abel) and of the liver (Abel), and a 
cloudy swelling of the liver and kidneys (Abel) which our mice failed to 
show. The macroscopic and microscopic changes which we found in the 
kidneys in mice, and also in some cases in the liver and spleen, were not ob- 
served by Fasching or by Abel. Recently Paulsen has described a capsule ba- 
cillus from atrophic rhinitis, and Marchand a capsule bacillus—not further 
described—which he obtained in great numbers from the exudate in a case 
of lobar pneumonia. Both appear to be very similar to Fasching’s bacillus. 
They are pathogenic for mice, but do not cause the changes in the kidneys 
which we have described. These capsule bacilli are therefore not identical 
with ours. Marchand’s bacillus is further distinguished by the fact that it is 
pathogenic for guinea-pigs. . . . The bacillus of Kockel is distinguished 
from ours by the following characters: It forms upon the surface of gelatin, 
as well as in stick cultures, highly elevated, button-like colonies, while our 
bacillus grows more in flat and broad layers. It also lacks the semi-fluid 
character of growth upon slanting agar, which distinguishes our bacillus, 
and as a result of which the growth slips down to the lowest point on the 
slanting surface ; further it forms upon potato a yellowish layer, while ours 
is grayish-white ; and it does not grow in acid media. Finally, it is patho- 
genic for rabbits by intravenous injection, while ours is not.” 
BACILLUS MUCOSUS OZANAL. 
Obtained by Abel (1893) from cases of ozeena simplex (rhinitis atrophicans 
foetida). As this bacillus appears to correspond in its morphological and bio- 
logical characters with the capsule bacillus above described we shall not 
repeat this description, but quote from Abel, as follows: 
“This bacillus. found in the secretion from cases of ozzena, as the de- 
scription we have given shows, closely resembles Friedlinder’s pneumo- 
bacillus. It is distinguished from it by certain constant characters. The 
ozeena bacillus forms in cultures a more fluid mass than Friedlander’s. As 
aresult of this it does not form the characteristic nail-head culture, but 
spreads out over the surface of the gelatin. Upon slanting gelatin cultures 
the growth slips down to the lowest point. In old cultures it never shows a 
brown coloring of the culture medium. It never forms gas on potato, and 
in agar and gelatin cultures but little gas is developed. Mice always suc- 
cumb to subcutaneous inoculations, while Friedlander’s bacillus does not 
kill mice. Intraperitoneal infection of guinea-pigs with the ozeena bacillus 
always causes their death. Friedlandev’s bacillus only killed about half the 
guinea-pigs inoculated in the cavity of the abdomen. Finally, Friedlander’s 
bacillus has a greater tendency to cocci-like forms. The resemblance to 
Pfeiffer’s capsule bacillus is closer. But the tenacious layer described by 
Pfeiffer as found upon the intestinal coils and the lungs in mice, and the 
sticky condition of the blood and tissue juices (fadenziehende) are want- 
ing. The reaction at the point of inoculation in mice is also much more 
pronounced with my bacillus.” ; 
It seems extremely probable that this bacillus,the Bacillus capsulatus mu- 
cosus of Fasching, and the above-described capsule bacillus of Nicolaier 
are simply pathogenic varieties of one and the same bacillus. 
36 
