PATHOGENIC ANAEROBIC BACILLI. 585 
a white color by reflected light. The culture medium acquires an acid re- 
action as a result of the development of the bacillus. ; ‘ 
Liver tissue containing this bacillus, after having been kept in an anti- 
septic wrapping for forty-eight hours, has a fresh appearance, a very acid re- 
action, and is without any putrefactive odor. 
Pathogenesis.—Liver tissue containing this bacillus is very pathogenic 
for guinea-pigs when injected subcutaneously, and causes an extensive in- 
flammatory edema extending from the point of inoculation. Pure cul- 
tures of the bacillus are less pathogenic, and the few experiments which I 
made in Havana gave a somewhat contradictory result, recovery having 
occurred in one guinea-pig which received a subcutaneous injection of ten 
minims of liquid from an anaérobic culture in glycerin-agar, while another 
died at the end of twenty hours from a subcutaneous injection of three 
apse ta extensive inflammatory cedema in the vicinity of the point of 
inoculation. 
BACILLUS OF SYMPTOMATIC ANTHRAX. 
Synonyms.—Rauschbrandbacillus, Ger. ; Bacille du charbon 
symptomatique, Fr. 
First described by Bollinger and Feser (1878); carefully studied 
and its principal characters determined by Arloing, Cornevin, and 
Thomas (1880-83). 
Fie. 167. Fic. 168. 
Fia. 167.—Bacillus of symptomatic anthrax, from an agar culture. x 1,000. From a photomi- 
erograph. (Frankel and Pfeiffer.) 
Fig. 168.—Bacillus of symptomatic anthrax, from muscles of inoculated guinea-pig. From a 
photomicrograph. (Roux.) 
Found in the affected tissues of animals—principally cattle—suf- 
fering from ‘‘ black leg,” “‘ quarter evil,” or symptomatic anthrax (Fr., 
‘‘charbon symptomatique”; Ger., ‘‘ Rauschbrand”). The disease 
