TOXICOLOGY 279 
orange colored. The blood is well coagulated and brownish red in 
color. 
BICHLORIDE OF MERCURY (MERCURIC CHLORIDE, CORROSIVE 
SUBLIMATE ) 
Lethal dose. 4 grains. 
Toxic dose. 4 grains. 
Non-toxic dose. 3 grains. 
1-6000 solution as drinking water for 18 days without harm. 
Experiments. (1) June 10, 1918, 10 a.m. Fowl received 5 
grains of bichloride of mercury. 10.45 a.m. Spasmodice move- 
ments of the crop for several minutes. 11.45 a.m. Droopy. 2 
p.m. Sitting. Legs weak. Drooping. 4P.m. Sitting. Cannot 
stand. Marked depression. June 11, 1918, 9:4.m. Fowl found 
dead. Autopsy notes. No food in crop. Gizzard filled with food. 
Mucous membrane of dependent portion of crop is whitened and thick- 
ened as a result of coagulation necrosis. Proventriculus shows severe 
catarrhal condition. Mucosa at entrance to gizzard is necrosed. 
Membrane of posterior portion of gizzard is separated from the giz- 
zard wall, the space being filled with clear fluid. Mucosa of first 
third of intestine is exfoliated and remainder of small intestine shows 
a severe catarrhal condition. Other organs apparently normal. 
(2) August 12, 1918, 2.20 p.m. Four pound fowl received 4 
grains of bichloride of mercury. 4.30 P.m. Nochange noted. Au- 
gust 13, 9 a.m. Legs very weak. Bird cannot walk. Sits down. 
Otherwise looks bright and normal. August 14,9 a.m. Fowl can- 
not stand. August 15,94.m. Fowldead. Autopsy notes. Small 
amount of oats in crop. Crop wall is thickened, pale; mucosa is 
coagulated. Subcutaneous tissue surrounding crop and esophagus 
is infiltrated with a greenish gelatinous exudate. Proventriculus 
shows several hemorrhagic points on mucosa. Gizzard contains a 
considerable quantity of greenish colored food. Mucosa of small in- 
testine is pale. Kidney is very pale and studded with minute white 
spots. Air sac membranes in abdominal cavity are thickened. The 
abdominal cavity contains 6 ounces of a thick somewhat viscid fluid 
with a slight greenish tinge. 
(3) February 28, 1918, 10 a.m. Fowl received a tablet contain- 
ing 3 grains of bichloride of mercury and 3 grains of ammonium 
chloride. Result. No effect was apparent. 
