TKICHINIASIS — TRICHINOSIS. 



85 



this girl had some time pi-eviously eaten a quantity of raw ham. Yirehow 

 and Leuckart returned to their investigations, and the hie history of the 

 parasite soon became definitely known. 



Causation. Trichinosis is capable of attacking all mammifers with- 

 out exception, from a man to a mouse ; and most animals which can be 

 made the subjects of experiment contract the disease in varying <legrees. 



The intestinal form is seen in birds, but the muscles do not become 

 infested by the embryos. 



Cold-blooded animals are proof against the disease. 



After the ingestion of meat containing cysts of the parasite, the 

 processes of gastric and intestinal digestion set the larvis at liberty. 

 These larvas become sexual at the end of four 

 to five days, and the females, which are usually 

 twice as numerous as the males, begin laying 

 eggs from the sixth day, continuing for a 

 month to six weeks. Each female lays 

 approximately from 10,000 to 15,000 eggs. 

 The embryos perforate the intestinal walls, 

 pass into the circulation, and are hurried into 

 all parts of the system. This period of infes- 

 tation coirstitutes the first phase of the disease. 



Askanazy, in 1896, suggested that it was 

 not the embryos which perforated the intes- 

 tinal walls and thus reached the blood-vessels, 

 but the fertilised female trichina themselves, 

 which entered the terminal chyle vessels and 

 laid their eggs directly within them. 



This observation is of great interest, for 

 it contradicts the view held by Leuckart and 

 proves that treatment is useless even in the 

 first phase. 



The males are about jV i"ch in length, the females ^ inch to ,^ inch, 



and are ovoviviparous. 



Symptoms. The symptoms lack precise character, even when the 

 disease is known to be developing, and moreover they have only been 

 carefully observed in experimental cases. As soon as the laying period 

 begins, signs of intestinal disturbance may be observed, possibly due to 

 embryos perforating the intestinal waUs (if we accept Leuckarfs view), or, 

 according to Askanazy, to adult females penetrating the chyle vessels and 

 disturbing intestinal absorption. 



These symptoms are only appi-eciable in cases of " massive " infesta- 

 tion If slight, the disturbance passes unperceived. In severe cases 

 the symptoms consist of diarrhcea, loss of appetite, grinding of the teeth, 



Fk;. 46. — Wale trichina from 

 the intestine. (Colin.) 



