INFECTIOUS DISEASES. 555 
case, too, for a few days the submaxillary space may so swell as to 
resemble the edematous, inflamed glands of strangles, equine variola, 
or laryngitis. This condition is especially liable to be marked in an 
acute outbreak of glanders in a drove of mules. 
Cases of chronic farcy and glanders, if not destroyed, may live in 
a depraved condition until the animal dies from general emaciation 
and anemia, but in the majority of cases, from some sudden exposure 
to cold, it develops an acute pneumonia or other simple inflammatory 
trouble which starts the latent disease and the animal has acute 
glanders. 
In the ass, mule, and plethoric horses acute glanders usually termi- 
nates by lobular pneumonia. In other cases the general symptoms 
may subside. The symptoms of pneumonia gradually disappear, the 
temperature lowers, the pulse becomes slower, the ulcers heal, leaving 
small, indurated cicatrices, and the animal may return to apparent 
health, or may at least be able to do a small amount of work with but 
a few symptoms of the disease remaining in a chronic form. During 
the attack of acute glanders the inflammation of the nasal cavities 
frequently spreads into the sinuses or air cells, which are found in the 
forehead and in front of the eyes on either side of the face, and causes 
abscesses of these cavities, which may remain as the only visible symp- 
tom of the disease. An animal which has recovered from a case of 
acute glanders, like the animals which are affected by chronic gland- 
ers and chronic farcy, is liable to be affected with emphysema, of the 
lungs (heaves), and to have a chronic cough. In this condition it 
may continue for a long period, serving as a dangerous source of con- 
tagion, the more so because the slight quantity of discharge does not 
serve as a warning to the owner or driver as profuse discharge does 
in the more acute cases. 
At the post-mortem examination of an animal which has been de- 
stroyed or has died of glanders we find evidences of the various 
lesions which we have studied in the symptoms. In addition to this, 
we find nodules similar to those which we have seen on the exterior 
throughout the various organs of the body. Nodules may be found 
in the liver, in the spleen, and in the kidneys. We may find inflam- 
mation of the periosteum of the bones, and we have excessive altera- 
tions in the marrow in the interior of the bones themselves. Both 
these conditions during the life of the animal may have been the 
cause of the lamenesses which were difficult to diagnose. 
In one case which came under the observation of the writer, a lame 
horse was destroyed and found to have a large abscess of the bone of 
the arm, with old nodules of the lungs. When an animal has died 
immediately after an attack of a primary, acute case of. glanders, we 
find small V-shaped spots of acute pneumonia in the lungs. If the 
animal has made an apparent recovery from acute glanders, and in 
