346 SMAix-POx. 



surrounded by a red areola and their center was flattened. 

 They were larger than an ordinary lentil. In some animals 

 they were confiaed to a few spots, in others they spread over 

 the whole body. They were scattered here and there, or 

 disposed in. the form of beads, or congregated together in a 

 mass. 



" When the disease was not of an acute character, and the 

 eruption was not considerable, and the febrile symptoms were 

 mitigated as soon as the pustule was developed, there was 

 not much to fear. The eruption ran through its several 

 stages, and no serious disorganization remained ; but in too 

 many cases the whole of the integument became reddened and 

 inflamed, the flanks heaved, the pulse, whether strong or 

 obscure, increased in frequency, the mouth was hot, the 

 conjunctiva red, the breath fetid, the head swelled, the eye- 

 lids almost closed; rumination had ceased, the muscular 

 power was exhausted, the pustules died away with little 

 apparent fluid secretion, a fetid diarrhea ensued, and death 

 speedily took place. 



" The progress of the eruptive stage of the disease was 

 frequently, however, a very misatisfactory one. When the 

 pustule had risen, and the suppuration had commenced, a new 

 state of febrile excitement ensued, accompanied by more than 

 usual debility. It lasted from three to four days, and during 

 its continuance the pustules became whiter at their summit, 

 and the fluid which they contained was of a serous character, 

 yellow or red, transparent or viscid, and by degrees it 

 thickened and became opaque, and then puriform ; and at this 

 period, when danger was to be apprehended, a defluxion from 

 the nose ensued, and swellings about the head as already 

 described. 



" This was the contagious stage of the disease, and when 

 it was too easily and fatally transmissible by accidental 

 contact or by inoculation. 



" Then came the last stage, that of desiccation, and about 

 the twelfth day from the commencement of the disease. The 

 pustules subsided, or the integument gave way, and the fluid 

 which they contained escaped, and a scab was formed of 

 greater or less size and density, yellow or black, and which 

 detached itself bodily, or crumbled away in minute particles 

 or powder. The contagion was now at an end, and the 

 animal recovered his appetite and spirits and strength. This 

 stage of desquamation frequently lasted three weeks or a 

 month. 



