G@LANDERS. 217 
der, if one which involves so many and such various structures is to be 
regarded as a strictly local affection ? 
A horse, full of corn, and in the prime of health, if unfortunately 
inoculated with the virus of glanders, gencrally has the disease in its 
acutest form: the animal may be dead by the expiration of a week. 
Other quadrupeds, in which the disorder is provoked by natural causes, 
may, on the contrary, exhibit glanders in the most chronic shape. If 
the exciting cause has a strong con- 
stitution to act upon—especially 
if the horse, soon after imbibing 
the poison, be removed to easier 
work or a more dry abode—the 
malady may exist for years in a 
subtle, undeveloped form. A thin 
discharge only may run, irregu- ee eeMIseEReD) ESR GUGDERE. 
larly, from one nostril. At times 3: Zhe lvmnhatie gland cylmead hard, and edher 
no fluid may appear, nor is the 
liquid ever copious. One of the kernels, or lymphatic glands, situated 
between the branches of the channel, may be more or less fixed. But, 
otherwise, the horse is active, full of fire, and exhibits nothing to excite 
suspicion. During all this time the creature may be endowed with a 
fatal power of communicating the disease. Horses, having received the 
taint from such a source, may die within the week, while the cause of 
the mortality eats well, works well, delights the master’s eye by its 
thriving appearance, and in such a condition even may exist for years. 
In the early stage it is difficult to pronounce positively upon a case of 
glanders. Ulceration of the nasal membrane would be confirmation of 
the worst doubt; but the ulceration may be situated so high up as to 
defy all our efforts to distinguish it. Yet running from the nose may 
be perceptible, and the gland may he fixed to the jaw. Both of these 
symptoms, although lawfully provoking our fears, are frequently attend- 
ant upon aggravated or upon prolonged colds. The only lawful test, 
in such cases, is the administration of three doses of solution of aloes, 
eight ounces to the dose—allowing three days to elapse between each. 
If the horse be glandered, before the last purgative has set the real 
nature of the malady will be apparent in the aggravation of the symp- 
toms. If glanders be not present, a little careful nursing will generally 
remove all effect of the medicine. 
The glanders is mostly ushered in by febrile disturbance. The appetite 
is bad, the coat stares, and the pulse is quickened. A mash or two, 
however, apparently sets all right, and the matter is forgotten. Soon 
afterward a slight discharge may issue from one nostril; but it is so very 
