110 non-dysenteric patients, and as a control a series of 90 

 dysenteric cases also — only 200 cases in all. The 'dysenteric' 

 cases were all patients wLo had been invalided to England from 

 Gallipoli and Egypt suffering, or having recently suffered, from 

 ' dysentery ' — diagnosed, in most cases, on clinical grounds only. 

 The ' non-dysenteric ' class consisted of patients invalided from 

 the same areas for affections other than dysentery : but they 

 included 40 cases of non-dysenteric intestinal ailments — the 

 remaining 70 being wounded men and others with various non- 

 intestinal complaints. The results obtained from all these 

 different classes of patients were as follows : 



Infected with 

 Cases. No. examined. E. histolytica. 



All cases ... . .200 



Dysenteric ... 90 



Non-dysenteric ..... 110 



All intestinal ailments .... 130 

 All non-intestinal ailments . . 70 



per cent, 

 H.O 

 10.0 



11. a 



8.3 

 15-7 



So far as these figures went, therefore, they did not warrant, 

 the conclusion that the cases being returned to England labelled 

 ' dysentery ' were more heavily infected with E. histolytica than, 

 those who were coming here by reason of their wounds or other- 

 non-dysenteric disabilities. 



In the summer of 1916 I undertook, in collaboration with 

 Dr. A. C. Stevenson, the examination of another series of non-. 

 dysenteric cases — the convalescent typhoid and paratyphoid cases 

 at Homchurch D^p6t. . We examined the stools of 472 such 

 patients, and found that 9-74 per cent, of them were infected with. 

 E. histolytica. 



These observations were sufficient to indicate the importance 

 of making further investigations along similar lines : and accord-, 

 ingly I urged all the protozoologists whom I had trained for the 

 work of diagnosis at military hospitals to examine as many non-. 

 dysenteric cases as possible. Some of them did so, but owing to. 

 the requirements of the Army it was difficult to obtain adequate 

 material for investigation. , Mr. "W. 0. Redman King examined 

 the stools of non- dysenteric patients in Graylingwell Military- 

 Hospital, Chichester.^ He was able to study 59 men — mostly 

 wounded — and found 8-5 per cent, infected with E. histolytica. 

 Mr. E. E. Savage, at the 2nd Southern G-eneral Hospital, Bristol,^- 

 was also able to examine a number of paratyphoidal cases and 

 a few patients suffering from wounds and other non-intestinal 

 ailments, and obtained similar results. Miss M. "W". Jepps, at. 

 Hampstead Military Hospital,^ examined 65 soldiers invalided 

 for ' irritable heart ' ; and among these she found — after an 

 exhaustive inquiry^ — that no less than 24 were infected with. 

 E. histolytica. Some of these at least had never suffered from 

 dysentery or other intestinal ailment. A few other workers 

 made similar observations, but on a smaller scale. The most. 



1 See Dobell (1917), p. 59. » See Hall, Adam, and Savage (1916). 



' See Jepps and Meakins (1917;. 



