BACTERIOLOGY IN A NUTSHELL. 



First 



Symptoms 



Relieved. 



Failures 

 Explained. 



Influence on 

 Symptoms. 



INFLUENCE ON THE SYMPTOMS. 



All the symtoms were very markedly reduced 

 in from twenty-four to forty-eight hours after 

 the intraspinal injections of the serum, as a 

 general rule. First symptoms relieved are 

 coma, headache, delirium and insomnia; tem- 

 perature falls and sometimes becomes normal. 

 The fall of temperature and lessening of other 

 symptoms may come by lysis or by crisis. 

 Stiffness of the neck may persist longer than 

 the other symptoms although it is usually 

 relieved. Some cases are very little benefited 

 by the serum, others not at all. 



Sometimes the treatment is undertaken when 

 too late. Or the disease may be of the septic 

 type. Cases in which the disease is confined to 

 the cranial region, which the serum can only 

 reach with difficulty, are not apt to yield to 

 treatment. Another type not benefited is the 

 chronic type. Lesions are believed to be located 

 in the vertex or in the ventricles of the brain 

 and so are not so accessible to the serum. 



Stubborn cases lasting several weeks are not 

 so frequently found as they were before the 

 introduction of serum therapy. Convalescence 

 is shorter and less marked by listlessness, the 

 drawn and lifeless appearance of the face, etc. 

 The infrequency of after-effects is believed to 

 be due to the use of the serum not giving them 

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