150 THE LAND-MARKS OF 



IV. That after the development of symptoms of cobra- 

 poisoning, the injection of permanganate of potash, whe- 

 ther hypodermic or intravenous, or both, failed to exer- 

 cise any influence upon the symptoms. 



V. That permanganate of potash possesses no pro- 

 phylactic properties, since death followed the hypodermic 

 injection of three and a half centigrammes of cobra- 

 poison in watery solution in the case of a dog which had 

 been hypodermically injected a few hours previously 

 with 8 decigrammes of the agent in solution. 



VI. That it would appear to be absolutely necessary 

 that the permanganate to be efficacious should come 

 into actual contact with the cobra-poison. 



VII. That although no symptoms of cobra-poisoning 

 followed the injection of cobra-poison and permanganate 

 of potash, sloughing of the part injected sometimes fol- 

 lowed. 



VIII. That up to the present time it has never been 

 experimentally shewn that any agent has sither the 

 power to neutralise the cobra- poison lying in the tissues, 

 or to prevent death when four minutes had elapsed from 

 the time of injection of the poison to that of treatment. 



IX. That if permanganate of potash has such power 

 to destroy so subtle a poison as that of the cobra, it is 

 probable that the hypodermic injection of the agent, in 

 the bite of a rabid animal, would destroy the virus which 

 causes that terrible disease — Hydrophobia. 



