Inflammation. Phlogosis. Phlegmasia. 57 



skin are drawn in, so as to cover the wound more or less per- 

 fectly, and a slight scar only is left when healing has been 

 accomplished. 



Granule Corpuscles and Masses. This is another degener- 

 ative transformation in lymph and, is seen mainly in inflamed 

 glands and brain and lung-tissue. The cells found in the 

 exuded lymph are made up of granules jh^tttt i^i^h in diameter, 

 and besides these, large, irregularly shaped masses of granules 

 are extended along the capillary blood-vessels. After the lymph 

 has coagulated these granular masses soften and liquefy prelimi- 

 nary to re-absorption and removal, and the restoration of the tis- 

 sue to a healthy condition. When in excess this softens and dis- 

 integrates the tissues, leading to permanent loss of substance. 

 See granular degeneration. 



Interstitial Development of Lymph into Tissue. This 

 is equivalent to what takes place in the formation of the sac of 

 the abscess or of granulation- tissue. The liquid lymph in coagu- 

 lating, becomes fibrillar, and the cells and nuclei of the adjacent 

 tissue, having an abundant supply of blood and nutriment, multi- 

 ply first as simple, rounded, embryonic cells, then deposit around 

 them new tissue, becoming elongated, spindle-shaped, branching, 

 etc., and thus get imbedded in a fibrous material of their own 

 formation. These new formations are usually of a low type of 

 organization, like white fibrous tissye or bone, and hence, al- 

 though breaches in the higher structures like muscle, nerve, gland, 

 skin, are filled up, it is usually only by the drawing together of 

 the remaining healthy parts by these new formations without the 

 restoration of any of the original tissue which has been destroyed. 

 The cicatrix (scar), alone is made up of new material. 



I^ymph developing in this way may undergo any degeneration 

 to which normal tissues are subject. Thus it may undergo black, 

 pigmentary {melanotic) degeneration, it may become impregnated 

 with lime-salts {calcified') , it may wither up into a hard gelatini- 

 form or horny mass, or it may undeTgo fattj/ degeneration. 



Fatty degeneration is the most common form, and consists in 

 the excessive deposit of fatty granules, first in the cells which 

 are in excess or badly nourished, and next in the adjacent tissue, 

 the normal elements of which are replaced by fatty granules. 



Softening is an almost constant result of inflammation. The 

 exudate infiltrates and separates the tissue elements, destroying 



