258 Veterinary Medicine. 



This proved infecting to the ass, rabbit and Guinea,pig, while 

 the cat and white rat proved immune. Intratracheal injection 

 of the dog produced a transient pneumonia. The ass inoculated 

 with the blood of the infected rabbit died in three days, with a 

 hepatized lung, pleurisy, and swarms of the microbes in the lungs, 

 blood and internal organs. Rabbits injected intravenously had 

 enlarged spleen, reddish exudate in the serous cavities, urine 

 stained with haemoglobin, and lungs and kidneys congested. 

 With intratracheal injections the lesions were exclusively pul- 

 monary. The pulmonary lesions were less constant in the Guinea- 

 pig. Weakened virus caused pulmonary lesions only, without 

 septicaemia. Probably identical with Schiitz's germ. 



It has been suggested that this coccus is at least closely related 

 to that of pneumo-enteritis of the horse. 



Cocco-BACiLLUS OF LiGNiERES. I/ignieres found in the exu- 

 dation in the tissues in the early stages of contagious pneumonia, 

 influenza, and strangles, alike, a small cocco-bacillus, ovoid, tak- 

 ing polar stains especially, bleaching in Gram's or Wiegert's 

 (iodine) solutions, non-motile, non-sporulating, and non-liquefy- 

 ing. These are the characteristics of the microbes of septicaemia 

 hsemorrhagica, classed together as Pasteurella by Trevisan, and 

 producing in all cases very similar lesions. They are only to be 

 found in pneumonia in the earlier stages, up to the eighth, or at 

 most the fifteenth day, and though the pure cultures proved fatal 

 to inoculated solipeds, cattle, sheep, pigs, rodents, and birds, 

 these inoculated cases have not shown the extremely infectious 

 qualities, which are such marked features of strangles, contagious 

 pneumonia and influenza. Further, the acceptance of lyignieres' 

 cocco-bacillus as the common cause of these diseases is in direct 

 contradiction of all past experience of these diseases which shows 

 a constant succession of cases of strangles, influenza or conta- 

 gious pneumonia in any given epizootic, and not a complex mix- 

 ture of these three affections as would happen if they had one 

 common cause. The cocco-bacillus therefore can only be consid- 

 ered as a predisposing or accessory cause, while the real patho- 

 genic agent which gives each disease its individual characters, is 

 the microbe which is found associated with or succeeding the 

 organism of l,ignieres. 



In addition we must recognize the microbes which become 

 pathogenic and maintain pneumonia as they do bronchitis. 



