282 Veterinary Medicine. 



these microbial! products is shown by the fact that the subcu- 

 taneous injection of the exudate speedily killed a Guinea-pig. 



Diagnosis depends on the persistence of a capillary bronchitis, 

 the abundance and purulent character of the discharge, the 

 marked dyspncea and dullpess and the existence of limited lung 

 areas devoid of their normal resonance, and having a peripheral 

 crepitation. 



Lesions. The most marked lesions are ; ist the congestion 

 and exudation in the bronchioles, with swelling and disquamation 

 of the epithelium ; and 2nd the infiltration or hepatization of 

 limited areas of lung tissue, the boundaries of which are usually 

 conterminous with a lobule or a group of lobules attached to a 

 particular bronchitic tube. These consolidated areas are studded 

 with numerous minute, dirty white, or yellowish foci, each rep- 

 resenting a terminal bronchiole with its cluster of air sacs and 

 cells overdistended by the exudate. 



Course. The progress of broncho-pneumonia is variable and 

 somewhat uncertain. If the disease is arrested early, there is a 

 gradual subsidence of the high fever, of the phenomena of 

 broncho-pneumonia, of dyspncea and anorexia, and a steady im- 

 provement and convalescence follows. Though somewhat 

 further advanced the pneumonia may undergo resolution, the 

 exudate being absorbed, the symptoms gradually improve and 

 a complete recovery may have taken place in two weeks. Under 

 less happy conditions there may remain thickening of the bronchial 

 mucosa and submucosa, the latter even becoming fibroid in 

 undergoing organization, so that contraction of the affected 

 bronchium with wheezing results ; the epithelium may remain 

 swollen, proliferate rapidly and contribute to produce a chronic 

 discharge, or even an ulcer ; the tube may remain blocked lead- 

 ing to collapse of the dependent part of the lung ; fibroid or 

 other nodules may appear outside the bronchial walls, or swelling 

 or even abscess in the lymph glands, keeping up a chronic bron- 

 chitis, and by pressure on the vagus, recurrent or sympathetic 

 nerve, causing pulmonary congestion or laryngeal paralysis 

 (roaring) ; or abscesses or vomicae may form in the lungs giving 

 rise to profuse, chronic discharge and loss of condition, with, 

 it may be, infection of the pleura, or secondary abscesses in 

 others parts. In many cases extensive pulmonary emphysema 



