Lymphadenoma. Hodgkin's Disease. 537 



In one case Siedamgrotzky found adenoid hypertrophy of the 

 thymus in a cow, and adenoma of the kidneys similar to that of 

 the liver has been noticed. 



Similar adenoid hyperplasia has been found in the lungs, the 

 bronchial mucous membrane, the pleura, the mediastinal and 

 bronchial glands, and the pericardium. In man this has invaded 

 the nerve centres, and it seems that at any point where there is a 

 lymph gland or a lymph plexus this adenoid hyperplasia may 

 localize itself. 



Symptoms. The general symptoms of failing health are as 

 -described in leukaemia. The particular symptoms of this disease 

 consist in the recognition of the adenoid hyperplasia in the 

 absence of a marked leucocytosis. The submaxillary glands are 

 usually the first attacked, and the disease may, in the horse, be 

 confounded with glanders. There is, however, no pituitary dis- 

 charge nor ulcer, the glands are enlarged symmetrically on the 

 two sides, and a careful search will usually discover other groups 

 with similar symmetrical enlargement. The parotidean, the 

 pharyngeal, the prepectoral, the prescapular, the axillary, the 

 popliteal, the prefemoral, the post and premammary, and the 

 inguinal should be critically examined. The enlarged mesenteric 

 glands may be reached and detected by the hand engaged in the 

 rectum, or in the small animals by external palpation, as may 

 also the enlarged spleen or liver. 



The adenoid hyperplasia in the chest offers very obscure and 

 uncertain symptoms. The enlarged bronchial and mediastinal 

 glands may seriously interfere with the functions of the vagus 

 nerve, causing, in cattle, disturbed digestion and rumination and 

 tympanies, in horses stertorous breathing, and in the carnivora 

 and omnivora a tendency to vomiting. In animals generally the 

 pressure on the cardiac nerves leads to great i.ritability of the 

 heart, and violent action under any exertion. The prominent 

 ■dyspnoea in the advanced stages may be explained by these 

 thoracic hjrperplasiae. 



Nocard claims that the urine furnishes most important indica- 

 tions in its low specific gravity (horse i did), its constant acidity, 

 and in the almost entire absence in that of the horse of hip- 

 puric acid. When there is any suspicion of tuberculosis or 

 glanders, the tuberculin or mallein test will decide. 



