150 DISEASES OF THE CIRCULATORY APPARATUS. 



this clot was found five f ally developed filari* — three females an( 

 two males. The number of embryo filarise found in the blood wa; 

 enormous ; Eeicke estimated them to be aboui one million. Thi 

 affected heart is shown in Fig. 41. 



Fig. 41. 



Heart, with fllarla immitis in tiie ventricle (photograph). 



The clinical symptoms of this disease were very plainly seen ii 

 a case described by Deffe. This was a five-year-old Japanese dog 

 On post-mortem the right heart showed several dark red blood 

 clots and thrombus and nearly fifty examples of the filaria immitis 

 ranging from 12 to 30 cm. in length and gathered in balls. H 

 found also enormous quantities of the embryos in the blood ; a 

 many as fifty could be counted under one microscopic glass-slide 

 The following changes were found in the right heart : Hypei 

 trophy, thrombus, endocarditis, and thrombus in the arteries c 

 the lungs ; chronic interstitial nephritis in the kidneys, and 

 number of embryos in Bowman's capsule and the canals hoUowe 

 and distended in different portions. 



The most important clinical symptoms were great emaciatior 

 notwithstanding plenty of good food and a good appetite (th 

 appetite afterward disappeared) ; cough, weakness of the heart' 

 action (small, irregular pulse, varying in force) ; polyuria (tl 

 urine was light and contained epithelium of the kidneys and blac 

 der) ; hyaline and granular cylinders ; albumin; triple phosphai 

 crystals; pain in the posterior portion of the body, especial! 

 in the region of the kidneys, and slight paralysis. 



