232 DISEASES OF TRUE INFECTION. 



exudate. The bronchial lymphatics are infiltrated and tumefied, 

 and in rare cases purulent. 



The lesions of the digestive tract are principally confined to the 

 small intestine ; the mucous membranes are red, and numerous 

 ecchymosed spots are found, 9,nd decided hemorrhages in the sub- 

 mucous tissue. The follicles of the patches and solitary glands of 

 Payer are tumefied, sunken in the inflamed mucous membrane, and 

 superficial ulcerated spots are found over the entire length of the 

 intestine (Nocard and Leclainche). 



We find also more or less pathological alteration in the central 

 nervous system, such as hypersemia and small hemorrhages in the 

 coverings of the brain; cedema of the brain is sometimes present, 

 and serous infiltration into the subarachnoids. In the ventricles 

 and base of the skull we have more or less marked venous hyper- 

 emia, and in rare cases purulent meningitis. As a rule, the 

 spinal cord shows nothing abnormal except that it is pale and 

 seems soft and bloody in consistence. 



Under.the„micr.oscope decided changes have been noticed in the 

 brain. KolesnikofE detected an infiltration of brain-matter and 

 walls of the brain-vessels with lymphoid cells, as well as a dis- 

 tention of the capillaries and arteries. These were filled with red 

 and white blood-corpuscles. In the infiltrated walls of the vessels 

 of the brain were found dark-colored, brittle, homogeneous gran- 

 ulations and accumulations. Krajewski found also the perivas- 

 cular spaces and the ganglionic cells filled with lymphoid corpuscles, 

 and he mentions particularly that those cases had died without 

 showing any prominent nervous symptoms. Another observer 

 found inflammation of the spinal cord in acute nervous distemper, 

 in which there was marked hypersemia. He also found alterations 

 in the walls of the vessels, and an albuminous exudation in the 

 upper third part of the spinal cord along the bloodvessels, as well 

 as in the interstitial tissue of th» gray substance. In " chronic " 

 distemper we have found an interstitial myelitis with partial 

 atrophy of the spinal cord. [The translator questions very much 

 whether there is a condition that can truly be termed "chronic" 

 distemper; if so, he has failed to observe it. The conditions that 

 the author speaks of should more properly be called sequences of 

 the disease.] 



Other abnormal conditions are found in distemper, such as 



