64 



actually received 2.5 cc. of the blood serum of Cruz. (For details of 

 this filtration, see p. 62.) 



On September 16 there were no symptoms. 



September 17, at 7 a. m., he was found with a temperature of 39.5° 

 C, with marked frontal headache, pains in the loins and calves of the 

 legs. His gums were slightly swollen and he had injection of the 

 ocular conjunctiva?. The patient said that at 1 o'clock in the morning 

 he felt like stretching and had a chill. The blood showed no malarial 

 parasites. Urine showed a trace of albumin. 



September 18 : Eyes and body jaundiced. 



The patient made a rapid recovery after a mild but definite attack 

 of yellow fever. 



German Ramos (case L), aged 22, single; has always lived in the 

 mountains near Puebla. He was given a careful physical examina- 

 tion August 26. Blood and urine negative. He was brought to Vera 

 Cruz August 28 and immediately placed in a mosquito-proof room, 

 where he was kept under observation eighteen days, when he was 

 given an injection of filtered serum, as follows: 



On September 15, at 4 p. m., he was given an injection into the 

 right median basilic vein of 5 cc. of diluted serum of Marcos Cruz, 

 filtered through a Pasteur-Chamberland filter B. This serum having 

 been diluted with an equal volume of physiological salt solution, 

 Ramos received 2.5 cc. of the serum of Cruz. (For details of this 

 filtration, see the records of Marcos Cruz, page 62.) 



September 16, no change. 



September 17, at 7 a. m., his temperature was 37.3° C, and he did 

 not feel at all unusual ; but at 9.15 a. m. his temperature was 39.4°. 

 He had frontal headache, pains in the back and calves of the legs. 

 The blood was negative for malaria. 



September 18, the eyes were injected and the body jaundiced. 

 Patient vomited twice. He exhibited a typical clinical picture of 

 yellow fever. 



His temperature on the third day was higher than at the onset of 

 the disease, which is rather unusual, and in Vera Cruz is considered 

 a grave sign. It will also be noted that his febrile period, which 

 lasted seven days, did not show the characteristic remission. Albu- 

 min first appeared on the 21st and continued until the 25th, when 

 examination was discontinued. 



Patient recovered. 



Guadalupe Gomez (case LI) ; born in Jalapa, aged 17, had never 

 been on the coast, and- states that he never had any kind of fever. He 

 was physically sound when examined ; blood and urine negative. He 

 was brought to Vera Cruz August 28 and placed in a mosquito-proof 

 room, where he was kept under observation eighteen days. 



