THE POISON OF THE HONEY-BEE. 23 



become more sensitive ; the head duller and tighter, 

 and the prostration more overpowering. In such a 

 case, Apis, prepared as above, became indispensable, 

 in order to remove all danger to life. Its curative 

 action soon became manifest in two different ways. 



If the reactive force of the organism was still 

 sufiELcient, the medicine succeeded very speedily in 

 preventing the supervention of the typhoid stage, 

 in changing the fever-type from a remittent or even 

 continuous to an intermittent type, during which 

 the convalescence of the patient, aided by a suita- 

 ble diet, was more and more firmly established and 

 generally completely secured after the lapse of a 

 week. 



If the typhoid stage could not be prevented and 

 set in with the following symptoms: the patient 

 lies on his bed in a state of apathy, with loss of re- 

 collection, sopor, muttering delirium, hardness of 

 hearing, inability to protrude the tongue or to 

 articidate; dry, cracked, sore, blistered, ulcerated 

 tongue ; dif&cult deglutition ; painful distention of 

 the abdomen, which is sensitive to contact or pres- 

 sure ; retention of stool, or else frequent, painful, 

 foul, bloody, involuntary diarrhoea; fermentous 

 urine, which is sometimes discharged involun- 

 tarily; the skin is at times and partially dry, 

 burning, at times and partially clammy, cool; 

 trembling and twitching of the limbs ; white mili- 

 aria on the chest and abdomen ; extreme debility, 

 with settling towards the foot-end of the bed ; 

 changing pulse, which is at times slow, at others 

 accelerated, feeble; intermittent: in such a case 



