Aspergillus Fumigatus, Lichtheim. 



Origin. — White bread; in the air passages and lungs of 

 birds; also met with in man. 



Color. — Greenish or bluish green growth, resembling 

 very much that of penicillium. 



Mycelium. — About the same as that of the preceding. 



Fruit-organs. — Like thei preceding, but the spores are 

 only about one-half 'as large and are usually colorless. 

 The sterigmas do not divide. 



Growth. — Is best on bread and is rapid. 



Bread tosfa.-^The growth'is low and at first bluish green, but 

 when old is grayish- green and resembles that of Penicillium. 



Temperature. — The optimum is 37-40°. It can grow at 

 the ordinary temperature, but not below 15°. 



Pathogenesis. -^Intravenous injections of millions of 

 spores in rabbits and dogs produced death in a few days. 

 Mycelia were found in the kidneys, heart and other muscles, 

 and occasionally in the liver. 



Infection of doves and other birds by inhalation of the 

 spores produces a pneumonic or pseudo-tuberculous disease. 

 Natural aflfections of this kind are frequently observed 

 among birds. Occasionally, they are met with in horses 

 and in cattle, and at times in man. 



In mycoses of man, the lungs, ears, eyes or nose are 

 subject to invasion. 



The Japanese utilize the growing A. Oryzae as a diasta- 



tic ferment, like malt. It converts rice grains into sugar 



and dextrin. This liquid is then subjected to fermentation 



and yields the national drink, Sake, which contains about 



14 per cent, of alcohol. Taka-diastase is a ferment derived 



from an aspergillus like that mentioned. 



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