201 



Serum of rabbit after one injection of B2 agglutinated in 1:320 

 dilution A, Bl, B2, C25, C56, and LL; did not agglutinate LP. 



Serum of rabbit after one injection of C25 gave exactly similar 

 results. 



Doctor Eeichel considers it proven that the organisms A to C55 

 are undoubtedly identical with Loeffler's bacillus of mouse typhoid, 

 and distinct from para-typhoid bacilli. The author considers it proven 

 that this bacillus was the sole cause of the cases of enteritis observed. 



Recently Mallory and Ordway '', in a paper read before the Ameri- 

 can Association of Pathologists and Bacteriologists held in Boston, 

 reported that lesions analogous to the early stages of typhoid lesions 

 may be produced in rats by the use of Danysz virus. 



In view of these facts the statements of some of the advertising 

 matter of certain rat viruses call for revision. 



REFERENCES TO THE LITERATURE. 



LoefHer,'" 1889, gives an account of two spontaneous outbreaks 

 among the mice kept at the Hygienic Institute at Griefswald. It was 

 from these animals that he obtained and described the original 

 B. typhi murium. He determined that the infection was by inges- 

 tion and that the organism was especially virulent for field mice. He 

 described the organism in detail and also the lesions. 



Laser,'' 1892, reports that on the morning of February 6, 1892, 

 70 of the 76 field mice ( Mus agrarius) used as experiment animals in 

 the Hygienic Institut at Konigsburg were found dead. A small 

 bacillus twice as long as broad, displaying a very lively specific motil- 

 ity, was isolated from the spleen. It was tested upon animals and 

 all the results compared with Eisenberg's tables and found to be 

 closely allied to the bacillus of ferret plague (Ebert-Schummelbusch), 

 to the bacillus of American swine plague (Billings), and to that of 

 French swine plague (Chantamesse and Cornil) . 



Mereshkowsky, ■* 1893, isolated an organism at the Royal Bac- 

 teriological Institute at St. Petersburg from a stock of Zisel {Spermo- 

 fhilus musicus) among which a spontaneous epizootic had occurred. 

 The author found this culture to be virulent for domestic and field 

 mice. 



^Mallory, F. B., & Ordway, T.: Lesions produced in the rat by a typhoidlike 

 organism (Danysz virus). Journ. Am. med. assn., vol. 52, May 1, 1909, p. 1455. 



b Loeffler, F.: Ueber Epidemieen unter den im hygienischen Institute zu Griefswald 

 gehalten Mausen und iiber die Bekamptung der Feldmausplage. Centblt. t. Bakt., 

 Orig., vol. 11, 1898, p. 129. 



c Laser, Hugo: Ein neuer fiir Versuchathiere pathogener Bacillus aus der Gruppe 

 derFrettschen-Schweinseuche. Centblt. f. Bakt., Orig., vol. 11, 1892, p. 184. 



<2 Mereshkowsky, S. S.. Ein aus Zieselmausen ausgeschiedener und zur Vertilgung 

 von Feld-resp. Mausen, geeigneter Bacillus. Centblt. f. Bakt., Orig., vol. 17, 1895, 

 p. 742. 



