CALCIUM CHLOEIDE 159 



The same comment applies to the administration of cal- 

 ciuni salts in delayed union in fractures and in anasmia, mal- 

 nutrition, and weakness of young animals. In the latter con- 

 ditions the calcium salt should be given with iron. 



Administration. — Precipitated calcium phosphate may 

 he given on the food, but is more readily absorbed if it is 

 administered in the syrup of calcium lactophosphate. 



Oalcii Chlokidum. Calcium Chloride. CaCL. 

 (U. S. & B. P.) 



Derivation. — Neutralize hydrochloric acid with cal- 

 cium carbonate and evaporate: 2 H ClXCaC03=CaCl2X 

 CO2 + H2O. Fusion at the lowest possible temperature 

 renders the salt" anhydrous. 



Properties. — White, translucent, hard fragments; odor- 

 less; having a sharp, saline taste, and very deliquescent. 

 Soluble in 1.3 part of water, in 8 parts of alcohol. 



Dose.—R. & C, § ss.-i. (15.-30.) ; D., gr.5-20 (.3-1.3). 



Actions and Uses. — Calcium chloride has been used of 

 late extensively both to prevent and arrest hemorrhage. 

 Outside of the body, calcium chloride causes blood to coagu- 

 late more quickly and firmly than usual, and the same kind 

 of action appears to obtain — i. e., rendering blood more 

 coagulable — when the salt is given internally. Calcium 

 chloride is an efiicient hemostatic in hematemesis, hemo- 

 ptysis, purpura hemorrhagica and in all conditions giving 

 rise to hemorrhage. When administered by the mouth 

 several days before surgical operations in maximum doses 

 it may lessen hemorrhage in cases likely to be attended by 

 much bleeding. Two per cent, solutions of gelatin in normal 

 salt solution have been given by the mouth, rectum and 

 subcutaneously for the same purposes, and it is thought 

 that the gelatin owes its power in arresting hemorrhage to 

 the calcium (0.6 per cent.) contained in it. Unless gelatin 

 is sterilized fractionally for half an hour on three to five 

 successive days, tetanus may ensue when it is injected under 

 the skin, and numerous cases have been reported following 

 such use in human surgery. The simplest manner of 

 employing gelatin to arrest hemorrhage internally is by 



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