354 VEGETABLE DRUGS 



Powdered opium, 4 ; benzoic acid, 4 ; camphor, 4; oil of anise, 4; 

 glycerin, 40; diluted alcohol to make 1000. Made by maceration and 

 filtration. (U. S. P.) 



Dose.— D., 3 i.-iv. (4.-15.). 



Opium Deodoratum. Deodorized Opium. (IT. S. P.) 



Synonym. — Opium denarcotizatum. 



Powdered opiuai (containing 12-13.5 per cent, of morphine), 500; 

 purified petroleum benzin, q. s. Made by repeated maceration, agita- 

 tion and percolation with purified petroleum benzin. The petroleum 

 benzin removts narcotic and odorous principles, which cause nausea 

 and disagreeable after-effects in opium. Contains 13-13.5 of morphine. 



Dose.— Same as powdered opium. 



The eighth (last) edition of the U. S. P. has introduced Opium 

 Oranulatum (granulated opium) ; made by drying opium at a tempera- 

 ture not exceeding 85° C. (185° F.) and reducing it to a coarse (No. 30) 

 powder. It should not yield less than 12 nor more than 13.5 per cent, 

 of crystallized morphine. Dose, same as deodorized opium. 



Tinctura Opii Deodorata. Tincture of Deodorized Opium. (U. S. P.) 

 Granulated opium, 100 ; purified petroleum benzin, 75 ; alcohol, 



300 ; water to make 1000. Made by percolation with water, agitation 



with purified petroleum benzin, and evaporation. 



Dose. — Same as tincture of opium, but less nauseating. 



Extractum Opii Liquidum. (B. P.) 



(Contains % per cent, of morphine.) 

 Dose. — Same aa laudanum. 



Vinum Opii. (U. S. P.) 

 Dose. — Same as laudanum. 



MoKPHiNA. Morphine. C^, H^, N O, -I- H, O. 



(U. S. & B. P.) 



Derivation. — Au alkaloid obtained from opium. 



1. Macerate opium in cold water, forming a solution of 

 morphine meconate. 2. Add calcium chloride to precipitate 

 calcium meconate and resins. 3. Evaporate solution remain- 

 ing, which contains morphine hydiochlorate, till it crystal- 

 lizes ; press in flannel to remove narcotine and coloring 

 matter ; redissolve ; filter ; evaporate and crystallize repeat- 

 edly. 4 Decolorize by digestion with charcoal. 5. Preci- 

 pitate with ammonia and wash, when pure morphine is 

 separated from codeine. 



Properties. — Colorless or white, shining prismatic crys- 

 tals, or fine needles, or crystalline powder ; odorless and 



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