MOEPHINE HYDBOCHLOEIDE 355 



having a bitter taste ; permanent in the air ; soluble in 4,350 

 parts of water. 



Dose. — Same as salts of morphine, but the latter are 

 preferable on account of their solubility. 



MoKPHiNa: Hydkochloeidum. Morphine Hydrochloride". 

 a,H,,N 0,H 01 + 3 H,0. (U. S. & B. P.) 



Derivation. — Morphine is stirred with hot distilled 

 ■water, to which hydrochloric acid is gradually added. Mor- 

 phine hydrochlorate crystallizes out on cooling. 



Properties. — White, feathery needles of a silky lustre ; 

 or minute, colorless, needle-shaped crystals ; odorless and 

 having a bitter taste. Permanent in the air. Soluble in 24 

 parts of water and in 62 parts of alcohol. Very slightly 

 soluble in ether or chloroform. 



Incompatibility. — Incompatible with all agents containing 

 tannin, alkaline carbonates, lime water, salts of copper, mer- 

 cury, zinc and lead ; and with Fowler's solution of arsenic. 



Dose.—B.. & C, gr.iii.-x. (.2-.6') ; Sh., gr.ss.-ii. (.03-.12) ; 

 Sw., gr.^V^ (.006-.08); D., gr.|-i (.008-.03). 



Subcutaneously.— H., gr.iii.-iv. (.2-.24); D., gr.|-^ (.008- 

 .03). 



124 parts of morphine hydrochloride correspond to 

 100 parts of morphine. 



MoEPHiN^ AcETAS. Morphine Acetate. 

 C„H,,N 0,C,H,0, + 3 H,0. (U. S. & B. P.) 



jjerivation. — Morphine is dissolved in acetic acid and 

 water, and the solution evaporated and crystallized. 



Properties. — A white, or faintly yellowish-white, crystal- 

 line, amorphous powder, having a faint, acetous odor and 

 bitter taste. It slowly loses acetic acid on exposure to the 

 air, and should be kept in dark, amber-colored, well-stop- 

 pered vials. Soluble, when freshly prepared, in 2.5 parts of 

 water, and in 47.6 parts of alcohol. 



Dose. — Same as morphine hydrochloride. 



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