392 VEGETABLE DBUGS 



Constituents. — The active principle of cannabis indica is 

 Cannabinol (O H COjoH^gC O H), a red oil or resin boiling 

 at a high temperature, which apparently exerts the charac- 

 teristic action (Marshall) of cannabis indica on man and 

 animals. But the therapeutic value of the principle has 

 not been sufficiently studied, to enable it to be used as a 

 substitute for the crude drug or its preparations. 



PRBPARA.TIONS. 



Extraotum Cannabis Indica. Extract of Indian Cannabis. 



(U. S. & B. P.) 

 Made by maceration and percolation with alcohol, and by evapora« 

 tion to a pilular consistence. 



Dose.—'B.., 3 i.-ii. (4.-8.); D., gr.J^-i. (.015-.06). 



Fluidextractwm Cannabis Indicce. 



Fluidextraot of Indian Cannabis. (U. S. P.) 



Made by maceration and percolation. The alcohol is distUled off 



from the last part of uUb percolate, aud the residue is dissolved in the 



first part (700 Cc), and enough alcohol is added to make 1 Cc. of the 



fluid extract equal 1 gm. of the crude drug. 



Dose.— a.. 3iv.-vi. (16.-24.); D., mii.-x. (.12-.6). 

 Administration. — The extract is given in ball, piU, electuary or 

 suppository ; ,or the fluid preparations may be used. 



Tinetura Cannabis Indicm. Tincture of Indian Cannabis. 

 (U. S. & B. P.) 



Indian cannabis, 100; alcohol to make 1,000 Cc. Made by macera- 

 tion and percolation. (TJ. S. P.) 

 Dose.— D., mxx.-xxx. (1.3-2.). 



Action External. — Cannabis indica exerts a considerable 

 irritant action when applied to mucous membranes. This 

 is followed by local anaesthesia. 



Action Interned. — Indian hemp is a distinct depressant 

 to the functions of the brain and cord in poisonous doses, 

 although therapeutically stimulating these organs in small 

 quantities, and producing in man a kind of intoxication and 

 mild delirium. The reflex activity of the spinal cord is 

 primarily increased, but this is succeeded by diminution of 

 reflex movement, and, after large doses, by anaesthesia and 

 loss of voluntary motion. The sensory tract (centres and 



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