VEBATKUM 463 



PEEPARATIONS. 



Fluidextractum Veratri. Fluidex-tract of Veratrum. 

 (U. S. P.) 

 Made by maceraticto and percolation with alcohol, and evaporation, 

 •0 that 1 cc. = 1 gm. of the crude drug. 



Dose.— H. & C, 3ss.-i. (3.-4.); Sh. &Sw., mxx.-xxx. (1.3.2.); D., 

 ni^j-i. (.006-.06). 



Tinetura Veratri. Tincture of Veratrum. 

 (U. S. &B. P.) 



Made by maceration and percolation of veratrum viride, 100 ; and 

 alcohol to make 1000. (U. S. P.) 



Dose.— H. & C, |ss.-i. (15.-30.); Sh. & Sw., 3ii.-iv. (8.-15.); D., 

 mv.-xv. (.3-1.) 



JEEVINE. 



Action Internal.-^Digestive Tract. — Large doses cause 

 salivation, but have little effect on the stomach or bowels. 



Circulation. — Jervine is a powerful depressant to the 

 heart muscle, its contained ganglia, and the vasomotor 

 centres. Large doses, therefore, weaken and slow the pulse 

 and lower vascular tension. 



Bespiration. — The alkaloid is also a profound respira- 

 tory depressant, and death occurs from asphyxia in poison- 

 ing, the heart continuing to beat after cessation of breathing. 



Nervous System. — In poisoning by jervine, animals 

 exhibit muscular tremors and weakness, and finally fall 

 from loss of muscular power. Lying prostrate on the 

 ground in a paralytic state, they are attacked by clonic con- 

 vulsions. The paralysis is attributable to depression of the 

 cells of the inferior cornua, while the convulsions are due to 

 disturbance of the cerebral circulation, or stimulation of the 

 cerebral motor tract. The muscles and nerves are unaffected 

 by jervine, but there is partial anaesthesia of spinal origin 

 observed just before death. 



VERATEOIDINE. 



Action Internal. — The alkaloid is a decided gastro-intes- 

 tinal irritant and produces Tomiting in animals capable of 

 the act, and often purging. 



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