478 VEGETABLE DRUGS 



(h) Less Important Constituents. — (5) Kinic, or quinic 

 acid (C,HijOj), occurs in colorless prisms. Eelated to benzoic 

 acid and eliminated in the urine as hippuricacid. Found in 

 coffee beans and other vegetables. 



The alkaloids in cinchona are naturally united with 

 kinic or kinovio acid, and salts of this combination are used 

 in medicine ; i.e., quinine kinate, which is soluble and may 

 be employed subcutaneously. 



(6) Kino vie, or quinovic acid (Cs^H^gOs), a white, amor- 

 phous substance allied to kinovin. 



(7) Kinovin, or quinovin (CjoH^Oe), a glucoside readily 

 decomposed into glucose and kinovic acid. 



(8) Cincho-tannic acid, or kiuo-tannic and kinovi-tannic . 

 acid (2-4 per cent.). The astringent principle of cinchona. 

 Distinguished from tannic acid in yielding green color with 

 ferric salts. 



(9) Cinchona red, the coloring matter of cinchona bark. 

 Nearly insoluble in water. 



(10) A volatile oil existing in minute amount. 



(11) Starch, gum, resin and salts common to other 

 vegetable matters. 



Incompatibility. — Cinchona is incompatible with lime 

 water, ammonia, metallic salts or gelatin. 



Dose.—B.., 3ii.-iv. (8.-15.); C, 5i.-ii. (30.-60.); Sh.&Sw., 

 3 i.-iv. (4.-15.) ; D. & C, gr.x.- 3 i. (.6-4.). 



PRBPAKATIONS. 



Fluidextr actum Cinchonce. Fluidextract of Cincliona. 

 (U. S. P.) 

 Made by maceration and percolation with glycerin, alcohol and 

 water ; evaporation of the last portion of the percolate, and addition of 

 the residue to first portion, with enough water and alcohol to make 

 1 oc. = 1 gm. of crude drug. Contains 4 per cent, of alkaloids. 

 (U. S. P.) 



Dose. — Same as cinchona. 



Extraotum Cinchonce Liquidum. (B. P.) 

 Contains 5 per cent, of alkaloids. 

 Dose. — Same as cinchona. 



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