TALLUNINE 545 



TaTiTiTANIKE. (Non-official.) 



Derivation. — Tallianine is said to be the result of the 

 action of ozone upon a terpin-bearing volatile oil, the action 

 being arrested at a point when the latter has absorbed a 

 quantity equal to four volumes of ozone. It is put on the 

 market in sealed glass tubes containing each 10 c.c. 



Properties. — A clear, colorless, slightly syrupy liquid, 

 having a strong odor of terpene and a taste both terebin- 

 thinate and saline. 



Z»ose.— (Intravenously) H. & C, 3iis.-v. (10-20 c.c); 

 Sh. & Sw., 11^75- 3 iiss. (5-10 c.c); D., nX30-75 (2-5 cc); 

 Cats, 11115-30 (1-2 cc). 



Actions and Uses. — External. — It has empirically given 

 the most favorable clinical results, according to recent 

 reports, in the moist and pustular forms of eczema when 

 applied once daily upon the skin in the pure state in con- 

 junction with the intravenous administration of 2 c.c. also 

 once daily, in the treatment of dogs. The skin should first 

 be well cleansed of dirt and sebaceous matter, with soap, 

 warm water and a scrubbing brush. There is no sort of 

 local reaction or 'disturbance when the drug is injected 

 intravenously. 



Internal. — Tallianine appears to be non-toxic in any 

 reasonable amounts ; 300 to 400 c.c. produce no untoward 

 effects when given intravenously to horses. The most pro- 

 nounced action of tallianine is exerted apparently upon the 

 blood. In ordinary doses it produces in the horse a leuco- 

 cytosis amounting to two or three times the normal and 

 within the space of two or three hours. The effect is the 

 same in large and small animals, although more rapid in the 

 latter. This action is maintained for from five to twenty 

 hours. The action of the heart seems to be moderately 

 stimulated, and also that of the kidneys, with accompanying 

 diuresis. The physiological details of these latter actions 



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