546 VEGETABLE DRUGS 



have not been worked out satisfactorily. The appetite is 

 also reported as being wonderfully improved under the 

 influence of the drug — whether directly or indirectly has 

 not been made clear. Tallianine is a French proprietary 

 preparation, and as such its chemistry and mode of manu- 

 facture have been withheld from the profession. Neither 

 has a thoroughly scientific study been made to determine 

 accurately its exact physiological action. The clinical re- 

 ports in this country and abroad have been so exceptionally 

 favorable that it was deemed proper to include the drug in 

 this work, notwithstanding our disinclination to include pro- 

 prietary preparations. Whether tallianine acts by virtue of its 

 ozonizing properties or by stimulating the phagocytic action 

 of the white blood cells in combating the micro-organisms 

 of disease or their toxins, or whether it is purely due to 

 altered metabolic activity, has yet to be determined ; but 

 clinically it has proven of great service in the following 

 diseases when given intravenously once (or in very severe 

 cases twice) daily, notably in pneumonia of all types, but 

 also in pleurisy, pulmonary congestion, bronchitis, influenza, 

 purpura hemorrhagica, heat apoplexy and prostration, 

 anasarca, tetanus and diphtheria. General improvement 

 with corresponding betterment in the .local pathological 

 conditions have been generally noted. Other medication 

 should be withheld. The types of disease benefited by 

 tallianine are so diverse that it is impossible to formulate a 

 logical theory as to its mode of action. We have only the 

 empirical, clinical results to base our remarks upon at 

 present, but these thus far give promise that we have in 

 tallianine a substantial addition to our pharmacopeia. 



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