SANTONICA 821 



ployed (with ^ part syrup of ginger) in three doses, at 

 hour intervals, for dogs. The patient should be previously 

 fasted for 24 hours, and castor oil is indicated if purging is 

 not produced by pomegranate. Tannate of pelletierine is a 

 yellowish, astringent-tasting powder, soluble in 12.6 parts of 

 alcohol and 235 parts of water. It is invariably used in 

 human medicine in preference to the crude drug, and should 

 be followed in 2 hours by a dose of castor oil. The use of 

 pelletierine is undesirable in young animals. 



Class 3.— Used to Destroy Round-Worms. 



t 



Santonica. Santonica. (U. S. & B. P.) 



Synonym. — Levant worm seed, semen cinse, s. contra, s. 

 sanctum, s. santonici, E.; barbotine, semencine, Pr.; wurm- 

 samen, zitwersamen, G.; flores cinse, P.G. 



The unexpanded flower-heads of Artemisia pauciflora 

 Weber (nat. ord. Compositas). 



Habitat. — Northern middle Europe and Asia. 



Description. — From 2 to 4 Mm. long ; oblong-ovoid, 

 obtuse, smooth, somewhat glossy, grayish-green, consisting 

 of an involucre of about 12 to 18 closely imbricated, glandu- 

 lar scales with a broad midrib, enclosing four or five rudi- 

 mentary florets ; odor strong, peculiar, somewhat camphor- 

 aceous ; taste aromatic and bitter. 



CoTistituents. — The active principle is (1) santonin. 

 There is also (2) a volatile oil. 



Santoninum. Santonin. G^^^f),. (TJ. S. & B. P.) 



Synonym. — Santonine, Fr.; santonin, G. 



A neutral principle obtained from santonica. 



Derivation, — Made from a mixture of lime and santonica 

 by exhausting with alcohol, evaporation of the latter, and by 

 the addition of acetic acid to the residue. Santonin is 

 obtained by treating an alcoholic solution of the residue with 

 animal charcoal and crystallization. 



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