632 VEGETABLE DEUGS 



Dose. — Golchicina, Colchicine (TJ.S.P.) — H. & C, gr.^|- 

 (.01-.03); D., gr.yl^-^ (.0005-.0012), by mouth or sub- 

 cutaneously. 



PREPARATIONS. 



Yinum Colchici Radicis. Wine of Colchicum Root. (Non-offioial.) 

 Made by percolation of oolchioum root (400) with alcohol (150), and 

 white wine to make 1000. 



Dose. — Twice that of colchicum corm. 



Vinum Colchici. (B. P.) 

 Dose. — Twice that of the root. 



Colchici Semen. Colcliicuni Seed. (U. S. P.) 



Synonym. — Colchici semina, B.P.; semences de col- 

 chique, Fr.; zeitlosensamen, G.; semen colchici, P.G. 



The seed of Colchicum autumnale Linne (nat. ord. 

 Liliacese). 



Description. — Subglobular, about 2 Mm. thick, . very 

 slightly pointed at the hilum ; reddish-brown, finely pitted, 

 internally whitish ; very hard and tough ; inodorous ; taste 

 bitter and somewhat acrid. » 



Constituents. — 1, colchicine, 3 per cent.; 2, colchiceine; 

 3, a fixed oil, 6-8 per cent.; 4, starch; 5, sugar ; 6, gum. 



Dose. — Same as corm, or a little larger. 



PREPARATIONS. 



Flmdextraetum Colchici Seminis. Fluidextract of Colchicum 

 Seed. (U. S. P.) 



Made by maceration and percolation with alcohol and water, and 

 evaporation, so that 1 cc. = 1 gm. of colchicum seeds. 



Dose.—R. & C, 3ss.-ii. (3.-8.); Sh., nix.-xx. (.6-1.3); Sw. &D., 

 niii.-viii. (.13-.5). 



Vinum Colchici Seminis. Wine of Colchicum Seed. (U. S. P.) 



Made by maceration of colchicum seed, 100 ; alcohol, 150 ; and 

 white wine to make 1000. 



Dose.— H.&C 3iii.-§i. (12.-30.); D., tiix.-xxx. (.6-2.). 



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