30 Harry C. Schmeisser. 
TABLE 1.—EXPERIMENTAL LEUKAIMIA. 
WEIcHTs, IN Grams or Bopy, ORGANS AND RELATION oF ORGANS TO Bopy 
AT AUTOPSY. 
aopmal Body. Liver. be Spleen. | § oe Kidneys. one 
Normal 1760 50 2.8 1 0.05 12 0.7 
1 1515 117 7.7 11 0.7 20 Lg 
6 1200 124 10.3 15 1,2 10 0.8 
12 sesh 95 caus 15 eeiere is licks 
14 1573 125 7.9 18 1.1 322 2.0 
15 1660 116 6.9 10 0.6 20 1.2 
248 ida ate Riles cr Be eee we 
28 897 85 9.6 6 0.7 
30 1410 107 7.6 17 0.6 ie eis 
31 675 20 2.9 3 4 5 0.7 
53 itera 265 exes 12 wa or Stee 
57 1070 91 8.5 18 1.6 15 1.4 
704 eras 65 or 4 ‘ii 26 Rebs 
103 1282 80 6.2 8 0.6 12 0.9 
1 Not weighed. 
2 Very edematous. 
3 Whole animal kept as a museum specimen. Illustrated, Fig. 5. 
4 Spontaneously cured. Not leukemic at death. 
SUMMARY. 
In summarizing the essential points deduced by the simple trans- 
mission of leukemia by the injection of an organic emulsion, we shall 
consider : 
1. Clinical History. After an incubation period, usually from five to 
six weeks, the fowl suddenly becomes pale, jaundiced, emaciates rapidly, 
loses weight and shows signs of extreme weakness, followed almost with- 
out exception by death in one to two weeks. 
2. Blood.—(a) The total number of white blood cells is greatly in- 
creased, resulting in a proportion of one white to three red blood cells. 
The differential count shows a marked increase and predominance of 
the large mononuclear over the other white cells of the normal blood, 
which have decreased. The mononuclear myelocyte with eosinophilic 
granules is present in more or less numbers in practically every case. 
Besides the normal-appearing large mononuclear, one sees many larger, 
pale forms. In these cells, mitoses, in all stages, typical and atypical. 
are common. (b) The total number of red blood cells is correspond- 
ingly decreased, with a marked fall in the hemoglobin. They present 
